CAS 2768502-17-4

Formula: C18H16N2O5

InChI: InChI=1S/C18H16N2O5/c21-16-7-5-11-4-6-14(9-15(11)20-16)25-10-17(22)19-13-3-1-2-12(8-13)18(23)24/h1-4,6,8-9H,5,7,10H2,(H,19,22)(H,20,21)(H,23,24)

InChI key: PCKIAYYPLYRMJK-UHFFFAOYSA-N

SMILES: C1CC(=O)NC2=C1C=CC(=C2)OCC(=O)NC3=CC=CC(=C3)C(=O)O

FXR agonist 11

CAS: 2768502-17-4

FXR agonist11 (Compound 14) is an FXR activator with an EC50 of 1.2 μM and a maximal effect of 73.7%. It significantly increases GSH levels in the liver and is used to study drug-induced liver injury.

Formula: C₁₈H₁₆N₂O₅

Color and Shape: Solid

Molecular weight: 340.33

Ref: TM-T203206