CAS 2799-07-7

S-Trityl-L-cysteine

Description:

S-Trityl-L-cysteine is a derivative of the amino acid cysteine, characterized by the presence of a trityl group, which enhances its stability and solubility. This compound is notable for its thiol (-SH) functional group, which plays a crucial role in redox reactions and can form disulfide bonds, making it significant in biochemical processes. S-Trityl-L-cysteine is often utilized in peptide synthesis and as a protecting group for cysteine residues in various chemical reactions, allowing for selective modifications without interfering with other functional groups. Its trityl group provides steric hindrance, which can influence the reactivity and conformation of the molecule. Additionally, this compound is soluble in organic solvents, facilitating its use in various laboratory applications. Due to its unique properties, S-Trityl-L-cysteine is valuable in both synthetic organic chemistry and biochemistry, particularly in the development of pharmaceuticals and research involving protein engineering.

Formula: C₂₂H₂₁NO₂S

InChI: InChI=1S/C22H21NO2S/c23-20(21(24)25)16-26-22(17-10-4-1-5-11-17,18-12-6-2-7-13-18)19-14-8-3-9-15-19/h1-15,20H,16,23H2,(H,24,25)/t20-/m0/s1

InChI key: InChIKey=DLMYFMLKORXJPO-FQEVSTJZSA-N

SMILES: C(SC[C@@H](C(O)=O)N)(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3

Synonyms:

• (2R)-2-Amino-3-[(triphenylmethyl)sulfanyl]propanoic acid
• (2R)-2-Amino-3-[(triphenylmethyl)thio]propanoic acid
• (2R)-2-Azaniumyl-3-tritylsulfanylpropanoate
• 3-Tritylthio-<span class="text-smallcaps">L</span>-alanine
• <span class="text-smallcaps">L</span>-Cysteine, S-(triphenylmethyl)-
• Alanine, 3-(tritylthio)-, <span class="text-smallcaps">L</span>-
• H-Cys(Trt)-OH
• NSC 83265
• S-(Triphenylmethyl)-<span class="text-smallcaps">L</span>-cysteine
• S-Triphenylmethyl-L-cysteine
• S-Trityl-(R)-cysteine
• S-Trityl-<span class="text-smallcaps">L</span>-cysteine
• S-tritylcysteine
• Tritylthioalanine
• S-Trityl-L-cysteine
• L-Cysteine, S-(triphenylmethyl)-

S-Trityl-L-cysteine

CAS: 2799-07-7

Formula: C₂₂H₂₁NO₂S

Purity: >95.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 363.48

Ref: 3B-T2522

(+)-S-Trityl-L-cysteine, 97%

CAS: 2799-07-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₂H₂₁NO₂S

Purity: 97%

Color and Shape: White to pale cream, Powder

Molecular weight: 363.48

Ref: 02-L14384

H-Cys(Trt)-OH

CAS: 2799-07-7

Cys(Trt)-containing peptides can be converted in high yields into the corresponding cystine peptides by iodine oxidation. Cys(Trt) (STLC, NSC 83265) is a reversible, tight binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression.

Formula: C₂₂H₂₁NO₂S

Purity: 94.13%

Color and Shape: White

Molecular weight: 363.48

Ref: 01-4001485

H-Cys(Trt)-OH

CAS: 2799-07-7

Formula: C₂₂H₂₁NO₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 363.4726

Ref: IN-DA00I59I

(+)-S-Trityl-L-cysteine

CAS: 2799-07-7

Formula: C₂₂H₂₁NO₂S

Purity: ≥ 95.0%

Color and Shape: White powder

Molecular weight: 363.48

Ref: 7W-GM5683

(+)-S-Trityl-L-cysteine

CAS: 2799-07-7

(+)-S-Trityl-L-cysteine

Purity: 98%

Molecular weight: 363.47g/mol

Ref: 54-OR1007786

S-trityl-L-Cysteine

CAS: 2799-07-7

S-trityl-L-Cysteine

Purity: ≥95%

Molecular weight: 363.47g/mol

Ref: 54-BUP13869

S-trityl-L-Cysteine

CAS: 2799-07-7

S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5

Formula: C₂₂H₂₁NO₂S

Purity: 97.02%

Color and Shape: Almost White To Light Yellow Granular Powder

Molecular weight: 363.47

Ref: TM-T36816

S-Trityl-L-cysteine - animal origin

CAS: 2799-07-7

Animal origin

Formula: C₂₂H₂₁NO₂S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 363.47 g/mol

Ref: 3D-FT28609

S-Trityl-L-cysteine

CAS: 2799-07-7

M03084 - S-Trityl-L-cysteine

Formula: C₂₂H₂₁NO₂S

Purity: 95%

Color and Shape: Solid, Powder or Crystalline Powder or Solid or Chunks

Molecular weight: 363.48

Ref: 10-M03084

S-Trityl-L-cysteine

Controlled Product

CAS: 2799-07-7

Applications A protected cysteine for peptide synthesis. S-Trityl-L-cysteine (STLC) is a tight-binding inhibitor of Eg5 that prevents mitotic progression. It has proven antitumor activity as shown in the NCI 60 tumor cell line screen.
References Brier, S., et al.: Biochemistry, 43, 13072 (2004), Sakowicz, R., et al.: Cancer Res., 64, 3276 (2004), Zhu, C., et al.: Mol. Biol. Cell, 16, 3187 (2005),

Formula: C₂₂H₂₁NO₂S

Color and Shape: Neat

Molecular weight: 363.47

Ref: TR-T887350

S-Trityl-L-Cysteine extrapure, 98%

CAS: 2799-07-7

Formula: C₂₂H₂₁NO₂S

Purity: min. 98%

Color and Shape: White, Powder

Molecular weight: 363.48

Ref: SR-48445