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CAS 2801785-12-4

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  • FAK-IN-26
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    FAK-IN-26

    CAS:
    <p>FAK-IN-26 is a blood-brain barrier-penetrating inhibitor of Focal Adhesion Kinase (FAK) with an IC50 of 0.87 nM. It significantly reduces tumor cell viability, cancer stem cell activity, and cell migration in A549 and SKOV-3 cell lines. FAK-IN-26 exhibits potent anticancer activity, achieving tumor inhibition rates of 59.15% and 57.9% in A549 and SKOV-3 tumor mouse models, respectively.</p>
    Formula:C20H19BrFN5O2
    Color and Shape:Solid
    Molecular weight:460.30

    Ref: TM-T207475