CAS 2819999-00-1

Formula: C23H26ClF3N6O4

InChI: InChI=1S/C23H26ClF3N6O4/c24-14-9-18-21(28-10-14)33-6-5-31(12-15(33)2-8-37-18)19(34)3-7-36-13-16-1-4-32(16)17-11-29-30-22(35)20(17)23(25,26)27/h9-11,15-16H,1-8,12-13H2,(H,30,35)/t15-,16-/m0/s1

InChI key: YSVWRWHSYZIFDS-HOTGVXAUSA-N

SMILES: C1CN([C@@H]1COCCC(=O)N2CCN3[C@H](C2)CCOC4=C3N=CC(=C4)Cl)C5=C(C(=O)NN=C5)C(F)(F)F

PARP7-IN-18

CAS: 2819999-00-1

Parp7-in-18 (Compound 8) is a selective PARP7 inhibitor with an IC50 of 0.11 nM, demonstrating strong anticancer activity and favorable pharmacokinetic properties [1].

Formula: C₂₃H₂₆ClF₃N₆O₄

Molecular weight: 542.94

Ref: TM-T87107