CAS 2820501-20-8

2,6-Piperidinedione, 3-[2,6-difluoro-4-[3-(hydroxymethyl)-1-azetidinyl]phenyl]-

Description:

2,6-Piperidinedione, 3-[2,6-difluoro-4-[3-(hydroxymethyl)-1-azetidinyl]phenyl]- is a complex organic compound characterized by its piperidine and azetidine moieties, which contribute to its structural and functional properties. The presence of difluoro substituents on the phenyl ring enhances its lipophilicity and may influence its biological activity. The hydroxymethyl group provides potential for hydrogen bonding, which can affect solubility and reactivity. This compound is likely to exhibit specific pharmacological properties, making it of interest in medicinal chemistry, particularly in the development of therapeutic agents. Its molecular structure suggests potential interactions with biological targets, and the presence of fluorine atoms may enhance metabolic stability. As with many compounds in this class, careful consideration of its synthesis, stability, and reactivity is essential for applications in drug development or chemical research. Safety and handling precautions should be observed due to the potential biological activity and chemical reactivity associated with its functional groups.

Formula: C₁₅H₁₆F₂N₂O₃

Synonyms:

• 2,6-Piperidinedione, 3-[2,6-difluoro-4-[3-(hydroxymethyl)-1-azetidinyl]phenyl]-

CRBN ligand-12

CAS: 2820501-20-8

CRBN ligand-12 (Compound 9) is a ligand for the CRBN-type E3 ubiquitin ligase. It is utilized in the preparation of PROTAC.

Formula: C₁₅H₁₆F₂N₂O₃

Color and Shape: Solid

Molecular weight: 310.296

Ref: TM-T205149