CAS: 285983-48-4 - Doramapimod

Formula: C₃₁H₃₇N₅O₃

InChI: InChI=1S/C31H37N5O3/c1-22-9-11-23(12-10-22)36-29(21-28(34-36)31(2,3)4)33-30(37)32-26-13-14-27(25-8-6-5-7-24(25)26)39-20-17-35-15-18-38-19-16-35/h5-14,21H,15-20H2,1-4H3,(H2,32,33,37)

InChI key: InChIKey=MVCOAUNKQVWQHZ-UHFFFAOYSA-N

SMILES: O=C(NC1=CC=C(OCCN2CCOCC2)C=3C=CC=CC13)NC4=CC(=NN4C5=CC=C(C=C5)C)C(C)(C)C

Synonyms:

• 1-(3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl)-3-(4-(2-(morpholin-4-yl)ethoxy)naphthalen-1-yl)urea
• 1-[2-(4-Methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea
• 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-{4-[2-(morpholin-4-yl)ethoxy]naphthalen-1-yl}urea
• 1-[5-Tert-Butyl-2-(4-Methylphenyl)Pyrazol-3-Yl]-3-[4-(2-Morpholin-4-Ylethoxy)Naphthalen-1-Yl]Urea
• Birb 796
• Birb 796Bs
• Brb 796
• N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N′-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea
• Unc 10225354
• Unc10225354
• Urea, N-[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N′-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]-

Urea, N-[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]-

CAS: 285983-48-4

• Formula: C₃₁H₃₇N₅O₃
• Purity: ≥99%
• Color and Shape: Solid
• Molecular weight: 527.6572

Doramapimod

CAS: 285983-48-4

• Formula: C₃₁H₃₇N₅O₃
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 527.67

Doramapimod

CAS: 285983-48-4

• Formula: C₃₁H₃₇N₅O₃
• Purity: 99.9% (Typical Value in Batch COA)
• Color and Shape: off-white solid
• Molecular weight: 527.66g/mol

Doramapimod

CAS: 285983-48-4

Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but …

• Formula: C₃₁H₃₇N₅O₃
• Purity: 99.65%
• Color and Shape: Solid
• Molecular weight: 527.66

Doramapimod

CAS: 285983-48-4

Applications Doramapimod is a highly potent inhibitor of p38 mitogen-activated protein kinase (MAPK). Doramapimod is …

• Formula: C₃₁H₃₇N₅O₃
• Color and Shape: Pale Beige Solid
• Molecular weight: 527.66

Doramapimod

CAS: 285983-48-4

p38α MAP kinase inhibitor; JNK2α2 protein kinase inhibitor

• Formula: C₃₁H₃₇N₅O₃
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 527.66 g/mol