FAAH-IN-8, with the CAS number 2867633-84-7, is a selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH). This enzyme is responsible for the breakdown of endocannabinoids, which are lipid-based neurotransmitters that play a crucial role in various physiological processes, including pain sensation, mood regulation, and appetite control. By inhibiting FAAH, FAAH-IN-8 can increase the levels of endocannabinoids, potentially enhancing their therapeutic effects. The compound is characterized by its ability to modulate the endocannabinoid system, making it a subject of interest in research related to pain management, anxiety, and other neurological disorders. Additionally, FAAH-IN-8 is typically studied in the context of drug development for conditions where endocannabinoid signaling is disrupted. Its chemical structure and properties contribute to its specificity and efficacy as a FAAH inhibitor, although detailed physicochemical properties such as solubility, stability, and bioavailability would require further investigation in a laboratory setting.

FAAH-IN-8

2867633-84-7: FAAH-IN-8, with the CAS number 2867633-84-7, is a selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH). This enzyme is responsible for the breakdown of endocannabinoids, which are lipid-based neurotransmitters that play a crucial role in various physiological processes, including pain sensation, mood regulation, and appetite control. By inhibiting FAAH, FAAH-IN-8 can increase the levels of endocannabinoids, potentially enhancing their therapeutic effects. The compound is characterized by its ability to modulate the endocannabinoid system, making it a subject of interest in research related to pain management, anxiety, and other neurological disorders. Additionally, FAAH-IN-8 is typically studied in the context of drug development for conditions where endocannabinoid signaling is disrupted. Its chemical structure and properties contribute to its specificity and efficacy as a FAAH inhibitor, although detailed physicochemical properties such as solubility, stability, and bioavailability would require further investigation in a laboratory setting.

<p>FAAH-IN-8 (compound 11) is a competitive inhibitor of FAAH with an IC50 of 6.7 nM and a Ki of 5 nM. It exhibits high blood-brain permeability and a significant antioxidant profile without neurotoxicity [1].</p>

CAS 2867633-84-7

FAAH-IN-8

FAAH-IN-8

Ref: TM-T86397