CAS 2871056-82-3

Formula: C19H19N7O2

InChI: InChI=1S/C19H19N7O2/c1-27-15-3-2-4-16(28-13-5-11(21)6-13)19(15)14-7-17(26-25-14)24-18-10-22-12(8-20)9-23-18/h2-4,7,9-11,13H,5-6,21H2,1H3,(H2,23,24,25,26)

InChI key: ZUNOPUCDGHVJOF-UHFFFAOYSA-N

SMILES: COC1=C(C(=CC=C1)OC2CC(C2)N)C3=CC(=NN3)NC4=NC=C(N=C4)C#N

BBI-355

CAS: 2871056-82-3

BBI-355 is an oral, potent, and selective small molecule CHK1 inhibitor with an IC50 of 0.3 nM. It exhibits significant antitumor activity, both as a monotherapy and in combination with targeted therapies, across various ecDNA+ oncogene-amplified tumor models.

Formula: C₁₉H₁₉N₇O₂

Color and Shape: Solid

Molecular weight: 377.40

Ref: TM-T207786