CAS 28860-95-9

Carbidopa

Description:

Carbidopa is a pharmaceutical compound primarily used in the treatment of Parkinson's disease and its symptoms. It functions as a dopa decarboxylase inhibitor, which prevents the conversion of levodopa to dopamine in the peripheral tissues, thereby increasing the availability of levodopa to the brain where it can be converted to dopamine. This mechanism enhances the therapeutic effects of levodopa while minimizing side effects such as nausea and vomiting. Carbidopa is often administered in combination with levodopa to improve the efficacy of treatment. The compound is characterized by its molecular formula, which includes carbon, hydrogen, nitrogen, and oxygen atoms. It is typically administered orally and is well-absorbed in the gastrointestinal tract. Carbidopa has a relatively low toxicity profile, but it may cause side effects such as dizziness, dry mouth, or dyskinesia in some patients. Its pharmacokinetics involve rapid absorption and a relatively short half-life, necessitating multiple doses throughout the day for optimal therapeutic effect.

Formula:C₁₀H₁₄N₂O₄

InChI:InChI=1S/C10H14N2O4/c1-10(12-11,9(15)16)5-6-2-3-7(13)8(14)4-6/h2-4,12-14H,5,11H2,1H3,(H,15,16)/t10-/m0/s1

InChI key:InChIKey=TZFNLOMSOLWIDK-JTQLQIEISA-N

SMILES:[C@@](CC1=CC(O)=C(O)C=C1)(C(O)=O)(NN)C

Synonyms:

(-)-L-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinamic acid
(-)-L-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinnamic acid monohydrate
(-)-L-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinamic acid
(-)-L-α-Hydrazino-3,4-dihydroxy-α-methylhydrocinnamic acid monohydrate
(2S)-2-(Aminoazaniumyl)-3-(3,4-dihydroxyphenyl)-2-methylpropanoate
(2S)-3-(3,4-Dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
(S)-Carbidopa
(αS)-α-Hydrazinyl-3,4-dihydroxy-α-methylbenzenepropanoic acid
1-α-(3,4-Dihydroxybenzyl)-α-hydrazinopropionic acid
L-3-(3,4-Dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid
L-Carbidopa
L-α-(3,4-Dihydroxybenzyl)-α-hydrazinopropionic acid
L-α-Hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic acid
L-α-Hydrazino-α-methyl-3,4-dihydroxyphenylpropionic acid
L-α-Hydrazino-α-methyl-β-(3,4-dihydroxyphenyl)propionic acid
L-α-Methyl-α-hydrazino-3,4-dihydroxyphenylpropionic acid
L-α-Methyl-α-hydrazino-β-(3,4-dihydroxyphenyl)propionic acid
L-α-Methyl-β-(3,4-dihydroxyphenyl)-α-hydrazinopropionic acid
L-α-Methyldopahydrazine
Benzenepropanoic acid, α-hydrazino-3,4-dihydroxy-α-methyl-, (S)-
Benzenepropanoic acid, α-hydrazinyl-3,4-dihydroxy-α-methyl-, (αS)-
Cabidopa
Carbidopa
HMD
Hydrazino-α-methyldopa
Hydrocinnamic acid, α-hydrazino-3,4-dihydroxy-α-methyl-, L-
Hydrocinnamic acid, α-hydrazino-3,4-dihydroxy-α-methyl-, L-
L-3-(3,4-Dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid
L-α-(3,4-Dihydroxybenzyl)-α-hydrazinopropionic acid
L-α-Hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic acid
L-α-Hydrazino-α-methyl-3,4-dihydroxyphenylpropionic acid
L-α-Hydrazino-α-methyl-β-(3,4-dihydroxyphenyl)propionic acid
L-α-Methyl-α-hydrazino-3,4-dihydroxyphenylpropionic acid
L-α-Methyl-α-hydrazino-β-(3,4-dihydroxyphenyl)propionic acid
L-α-Methyl-β-(3,4-dihydroxyphenyl)-α-hydrazinopropionic acid
L-α-Methyldopahydrazine
Lodosin
Lodosyn
Mk 486
N-Aminomethyldopa
α-Hydrazino-α-methyl-β-(3,4-dihydroxyphenyl)propionic acid
α-Methyldopahydrazine
Benzenepropanoic acid, α-hydrazino-3,4-dihydroxy-α-methyl-, (αS)-
L-alpha-Methyldopahydrazine
3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methyl-propanoic acid
Tocris-0455
1-(Mesithylene-2-sulfonyl)-3-nitro-1,2,4-triazole
L-alpha-Methyl-alpha-hydrazino-beta-(3,4-dihydroxyphenylpropionic acid
Carbidopum [INN-Latin]
alpha-Hydrazino-alpha-methyl-beta-(3,4-dihydroxyphenyl)propionic acid
CCRIS 5093
3-(3,4-DIHYDROXY-PHENYL)-2-HYDRAZINO-2-METHYL-PROPIONIC ACID
(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid hydrate (1:1)
(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methyl-propanoic acid
SMR000058235
NCGC00024596-01
(-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid
alpha-hydrazino-3,4-dihydroxy-alpha-methyl-(S )-
Carbidopa anhydrous
Benzenepropanoic acid
alpha-Methyldopahydrazine
L-alpha-Methyl-beta-(3,4-dihydroxyphenyl)-alpha-hydrazinopropionic aci d
alpha-HYDRAZINO-3,4-DIHYDROXY-alpha-METHYL-L-KINSON
Hadrazino-alpha-methyldopa
MLS000069628
See more synonyms

Purity (%)

100

Found 10 products.

+ Info
Carbidopa Monohydrate
CAS:
- 28860-95-9
- 38821-49-7
Formula:C₁₀H₁₄N₂O₄·H₂O
Purity:>98.0%(T)(HPLC)
Color and Shape:White to Light yellow powder to crystaline
Molecular weight:244.25
Ref: 3B-C2450
100mg
37.00€
VAT not included
1g
198.00€
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(S)-3-(3,4-Dihydroxyphenyl)-2-Hydrazinyl-2-Methylpropanoic Acid
CAS:
- 28860-95-9
(S)-3-(3,4-Dihydroxyphenyl)-2-Hydrazinyl-2-Methylpropanoic Acid
Formula:C₁₀H₁₄N₂O₄
Purity:97%
Molecular weight:226.23
Ref: 54-OR1008689
100mg
164.00€
VAT not included
250mg
267.00€
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1g
500.00€
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5g
1,837.00€
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Carbidopa
CAS:
- 28860-95-9
Formula:C₁₀H₁₄N₂O₄
Purity:99%
Color and Shape:Solid
Molecular weight:226.2292
Ref: IN-DA00I5DW
1mg
47.00€
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10mg
53.00€
VAT not included
50mg
59.00€
VAT not included
250mg
68.00€
VAT not included
100mg
69.00€
VAT not included
1g
88.00€
VAT not included
5g
200.00€
VAT not included
25g
665.00€
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Carbidopa
CAS:
- 28860-95-9
Formula:C₁₀H₁₄N₂O₄
Color and Shape:White To Off-White Solid
Molecular weight:226.23
Ref: 4Z-C-212
5mg
To inquire
100mg
To inquire
10mg
343.00€
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25mg
436.00€
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50mg
623.00€
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Carbidopa
CAS:
- 28860-95-9
Carbidopa
Formula:C₁₀H₁₄N₂O₄
Purity:≥98%
Molecular weight:226.23
Ref: 54-BUP13336
5mg
51.00€
VAT not included
10mg
73.00€
VAT not included
25mg
97.00€
VAT not included
50mg
112.00€
VAT not included
100mg
137.00€
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500mg
319.00€
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(S)-(-)-Carbidopa-d3 H2O(ring-d3)
CAS:
- 28860-95-9
Formula:(HO)₂C₆D₃CH₂C(CH₃)(NHNH₂)COOH
Purity:98 atom % D
Color and Shape:White Solid
Molecular weight:229.11419
Ref: 3U-D6406
5mg
487.00€
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10mg
806.00€
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Carbidopa
CAS:
- 28860-95-9
Carbidopa (Lodosyn) is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM).
Formula:C₁₀H₁₄N₂O₄
Purity:98.01% - ≥98%
Color and Shape:Solid
Molecular weight:226.23
Ref: TM-T6795
5mg
37.00€
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1mL*10mM (DMSO)
46.00€
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10mg
50.00€
VAT not included
25mg
65.00€
VAT not included
50mg
80.00€
VAT not included
100mg
96.00€
VAT not included
500mg
216.00€
VAT not included
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Carbidopa
CAS:
- 28860-95-9
Formula:C₁₀H₁₄N₂O₄
Molecular weight:226.23
Ref: ST-EA-CP-C54000
10mg
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25mg
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50mg
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100mg
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(S)-(-)-Carbidopa
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 28860-95-9
Stability Unstable in Solution
Applications (S)-(-)-Carbidopa is a peripheral decarboxylase inhibitor that is commonly used in combination with L-DOPA (D533751) for treatment of Parkinsonism. S(-)-Carbidopa ( has also been shown to prolong the elimination half-life of L-DOPA from blood plasma and skeletal muscle.
References Henry, G.M. et al.: Psychosom. Med., 38, 95 (1976); Leguire, L.E. et al.: Invest. Ophthalmol. Vis. Sci. 34, 3090 (1993); Deleu, D. et al.: Naun. Schmied. Arch. Pharmacol. 348: 576 (1993);
Formula:C₁₀H₁₄N₂O₄
Color and Shape:Neat
Molecular weight:226.23
Ref: TR-C175985
25mg
145.00€
VAT not included
100mg
208.00€
VAT not included
1g
291.00€
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+ Info
Carbidopa
CAS:
- 28860-95-9
Ref: BE-RMCC069000
1mg
28.00€
VAT not included

CAS 28860-95-9

Carbidopa

Carbidopa Monohydrate

Ref: 3B-C2450

(S)-3-(3,4-Dihydroxyphenyl)-2-Hydrazinyl-2-Methylpropanoic Acid

Ref: 54-OR1008689

Carbidopa

Ref: IN-DA00I5DW

Carbidopa

Ref: 4Z-C-212

Carbidopa

Ref: 54-BUP13336

(S)-(-)-Carbidopa-d3 H2O(ring-d3)

Ref: 3U-D6406

Carbidopa

Ref: TM-T6795

Carbidopa

Ref: ST-EA-CP-C54000

(S)-(-)-Carbidopa

Ref: TR-C175985

Carbidopa

Ref: BE-RMCC069000