CAS 289656-45-7: Senicapoc

Description: Senicapoc, with the CAS number 289656-45-7, is a chemical compound that functions primarily as a selective inhibitor of the KCa3.1 potassium channel. This compound has garnered attention in pharmacological research due to its potential therapeutic applications, particularly in the treatment of various diseases, including asthma and other inflammatory conditions. Senicapoc is characterized by its ability to modulate ion flow across cell membranes, which can influence cellular processes such as muscle contraction and immune response. The compound is typically studied in the context of its effects on smooth muscle cells and immune cells, where it may help to reduce hyperreactivity and inflammation. Its chemical structure includes specific functional groups that contribute to its biological activity and selectivity for the KCa3.1 channel. As with many pharmacological agents, the safety profile, pharmacokinetics, and potential side effects are critical areas of ongoing research to fully understand its therapeutic potential and limitations.

Formula: C₂₀H₁₅F₂NO

InChI: InChI=1S/C20H15F2NO/c21-17-10-6-15(7-11-17)20(19(23)24,14-4-2-1-3-5-14)16-8-12-18(22)13-9-16/h1-13H,(H2,23,24)

InChI key: InChIKey=SCTZUZTYRMOMKT-UHFFFAOYSA-N

SMILES: O=C(N)C(C=1C=CC=CC1)(C2=CC=C(F)C=C2)C3=CC=C(F)C=C3

Synonyms:

• 4-Fluoro-α-(4-fluorophenyl)-α-phenylbenzeneacetamide
• Benzeneacetamide, 4-fluoro-α-(4-fluorophenyl)-α-phenyl-
• Ica-17043
• Senicapoc
• 2,2-Bis(4-fluorophenyl)-2-phenylacetamide

Benzeneacetamide, 4-fluoro-α-(4-fluorophenyl)-α-phenyl-

CAS: 289656-45-7

• Formula: C₂₀H₁₅F₂NO
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 323.336

Senicapoc

CAS: 289656-45-7

• Purity: 99.5%
• Molecular weight: 323.34g/mol

2,2-Bis(4-Fluorophenyl)-2-Phenylacetamide

CAS: 289656-45-7

• Purity: 98%
• Molecular weight: 323.34g/mol

Senicapoc

CAS: 289656-45-7

Senicapoc (ICA-17043) blocks Gardos channel, reduces RBC dehydration, IC50: 11 nM for rubidium flux, 30 …

• Formula: C₂₀H₁₅F₂NO
• Purity: 95.7% - 99.47%
• Color and Shape: Solid
• Molecular weight: 323.34

2,2-Bis(4-fluorophenyl)-2-phenylacetamide

CAS: 289656-45-7

• Purity: 95.0%
• Molecular weight: 323.3429870605469

Senicapoc - Bio-X ™

CAS: 289656-45-7

This product is part of our Bio-X ™ Range. These products are aimed at life …

• Formula: C₂₀H₁₅F₂NO
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 323.34 g/mol

Senicapoc

CAS: 289656-45-7

Gardos channel inhibitor

• Formula: C₂₀H₁₅F₂NO
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 323.34 g/mol