CAS 290315-45-6

BMS-299897

Description:

BMS-299897, with the CAS number 290315-45-6, is a chemical compound that has been studied primarily for its potential therapeutic applications, particularly in the field of neuroscience. It is known to act as a selective antagonist of the dopamine D3 receptor, which is implicated in various neuropsychiatric disorders. The compound's structure features a distinct arrangement of functional groups that contribute to its biological activity and receptor selectivity. BMS-299897 has been evaluated in preclinical studies for its effects on behaviors related to addiction and mood disorders, showcasing its potential as a candidate for drug development. Additionally, its pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion, are crucial for understanding its efficacy and safety profile. Overall, BMS-299897 represents a significant interest in medicinal chemistry, particularly in the context of developing new treatments for conditions associated with dopamine dysregulation.

(R)-4-(2-(1-((4-Chloro-N-(2,5-difluorophenyl)phenyl)sulfonamido)ethyl)-5-fluorophenyl)butanoic acid

CAS: 290315-45-6

Formula: C₂₄H₂₁ClF₃NO₄S

Purity: %

Molecular weight: 511.9410

Ref: IN-DA002V9Y

BMS 299897

CAS: 290315-45-6

BMS 299897

Purity: ≥98%

Molecular weight: 511.94g/mol

Ref: 54-BUP06259

BMS 299897

Controlled Product

CAS: 290315-45-6

Formula: C₂₄H₂₁ClF₃NO₄S

Color and Shape: Neat

Molecular weight: 511.941

Ref: TR-B596070

BMS 299897

CAS: 290315-45-6

BMS 299897, a sulfonamide γ-secretase inhibitor, inhibits Aβ production with an IC50 of 7 nM in HEK293 cells overexpressing APP.

Formula: C₂₄H₂₁ClF₃NO₄S

Purity: 99.82%

Color and Shape: Solid

Molecular weight: 511.94

Ref: TM-T14673