CAS 29094-61-9

Glipizide

Description:

Glipizide is an oral hypoglycemic agent belonging to the sulfonylurea class, primarily used in the management of type 2 diabetes mellitus. Its chemical formula is C21H27N5O4S, and it functions by stimulating insulin secretion from the pancreatic beta cells, thereby lowering blood glucose levels. Glipizide is characterized by its relatively high solubility in organic solvents and moderate solubility in water, which influences its bioavailability and pharmacokinetics. The substance typically appears as a white to off-white crystalline powder. It has a molecular weight of approximately 445.54 g/mol. Glipizide is usually administered in tablet form and is known for its rapid absorption and onset of action, making it effective for controlling postprandial blood glucose levels. Common side effects may include hypoglycemia, weight gain, and gastrointestinal disturbances. As with any medication, it is essential for patients to follow their healthcare provider's guidance regarding dosage and administration to ensure safety and efficacy.

Formula: C₂₁H₂₇N₅O₄S

InChI: InChI=1S/C21H27N5O4S/c1-15-13-24-19(14-23-15)20(27)22-12-11-16-7-9-18(10-8-16)31(29,30)26-21(28)25-17-5-3-2-4-6-17/h7-10,13-14,17H,2-6,11-12H2,1H3,(H,22,27)(H2,25,26,28)

InChI key: InChIKey=ZJJXGWJIGJFDTL-UHFFFAOYSA-N

SMILES: S(NC(NC1CCCCC1)=O)(=O)(=O)C2=CC=C(CCNC(=O)C=3C=NC(C)=CN3)C=C2

Synonyms:

• 1-Cyclohexyl-3-((P-(2-(5-Methylpyrazinecarboxamido)Ethyl)Phenyl)Sulfonyl)Ure
• 2-Pyrazinecarboxamide, N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-5-methyl-
• Aldiab
• Cp 28720
• Digrin
• Dipazide
• Exylurea
• Glibenese
• Glibetin
• Glican
• Glidiab
• Glipid
• Glipizibe
• Glipizid
• Glipizida
• Glipizide(Usp)
• Gluco-Rite
• Glucolip
• Glucotrol
• Glucotrol Xl
• GlucotrolXL
• Glucozide
• Glupitel
• Glupizide
• Glyde
• Glydiazinamide
• Glynase
• K 4024
• K4024
• Melizide
• Mindiab
• Minidab
• Minidiab
• Minodiab
• N-(2-(4-(N-(Cyclohexylcarbamoyl)sulfamoyl)phenyl)ethyl)-5-methylpyrazine-2-carboxamide
• N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methylpyrazine-2-carboxamide
• N-(4-[β-(5-Methylpyrazine-2-carboxamido)ethyl]benzenesulfonyl)-N'-cyclohexylurea
• N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-5-methyl-piperazine-2-carboxamide
• N-[2-[4-[[[(Cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-5-methyl-2-pyrazinecarboxamide
• N-[2-[4-[[[(Cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]5-methylpyrazinecarboxamide
• Napizide
• Ozidia
• Pyrazinecarboxamide, N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-5-methyl-
• Samarium(III) ionophore I
• Semiglynase
• Sucrazide
• Tk 1320

Glipizide

CAS: 29094-61-9

Formula: C₂₁H₂₇N₅O₄S

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 445.54

Ref: 3B-G0369

Glipizide

CAS: 29094-61-9

An ATP-dependent potassium channel blocker

Formula: C₂₁H₂₇N₅O₄S

Molecular weight: 445.54

Ref: 02-J63398

GLIPIZIDE CRS

CAS: 29094-61-9

GLIPIZIDE CRS

Formula: C₂₁H₂₇N₅O₄S

Molecular weight: 445.5352

Ref: 41-G0340000

Glipizide

CAS: 29094-61-9

Sulfonamides used as drugs

Formula: C₂₁H₂₇N₅O₄S

Color and Shape: White Off-White Crystalline Powder

Molecular weight: 445.17838

Ref: 45-1292507

Glipizide

CAS: 29094-61-9

Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.

Formula: C₂₁H₂₇N₅O₄S

Purity: 99.67% - 99.75%

Color and Shape: Solid

Molecular weight: 445.54

Ref: TM-T1603

Glipizide

CAS: 29094-61-9

Formula: C₂₁H₂₇N₅O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 445.5352

Ref: IN-DA003QRJ

Glipizide

CAS: 29094-61-9

Formula: C₂₁H₂₇N₅O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 445.54

Ref: 4Z-G-112

Glipizide

CAS: 29094-61-9

Glipizide

Purity: 98%

Molecular weight: 445.54g/mol

Ref: 54-OR1029677

Glipizide

CAS: 29094-61-9

Formula: C₂₁H₂₇N₅O₄S

Purity: ≥ 98.0% (dried basis)

Color and Shape: White to off-white powder

Molecular weight: 445.54

Ref: 7W-GP6193

Glipizide

CAS: 29094-61-9

Glipizide

Purity: ≥98%

Molecular weight: 445.54g/mol

Ref: 54-BUP18542

Glipizide

CAS: 29094-61-9

Formula: C₂₁H₂₇N₅O₄S

Color and Shape: Neat

Molecular weight: 445.54

Ref: 04-C14025950

Glipizide 100 µg/mL in Acetonitrile

CAS: 29094-61-9

Formula: C₂₁H₂₇N₅O₄S

Color and Shape: Single Solution

Molecular weight: 445.54

Ref: 04-A14025950AL-100

Glipizide

CAS: 29094-61-9

Color and Shape: Neat

Ref: 86-MM0942.00

Glipizide Impurity 13

CAS: 29094-61-9

Formula: C₂₀H₃₃N₃O₆S

Molecular weight: 443.56

Ref: 4Z-G-1124

Glipizide

Controlled Product

CAS: 29094-61-9

Applications A sulfonylurea hypoglycemic agent. Used as an antidiabetic.
References Ambrogi, et al.: Arzneimittel-Forsch., 21, 200 (1971), Fuccella, et al.: J. Clin. Pharmacol., 13, 68 (1973), Brogden, R.N., et al.: Drugs, 18, 329 (1979), Lebovitz, H.E., et al.: Pharmacother., 5, 63 (1985)

Formula: C₂₁H₂₇N₅O₄S

Color and Shape: White

Molecular weight: 445.54

Ref: TR-G410225

Glipizide

CAS: 29094-61-9

Inhibitor of sulphonylurea receptor SUR1

Formula: C₂₁H₂₇N₅O₄S

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 445.54 g/mol

Ref: 3D-FG01273

GLIPIZIDE

CAS: 29094-61-9

Purity: 99%

Molecular weight: 445.5400085

Ref: 10-F857701