CAS 29094-61-9: Glipizide
Description:Glipizide is an oral hypoglycemic agent belonging to the sulfonylurea class, primarily used in the management of type 2 diabetes mellitus. Its chemical formula is C21H27N5O4S, and it functions by stimulating insulin secretion from the pancreatic beta cells, thereby lowering blood glucose levels. Glipizide is characterized by its relatively high solubility in organic solvents and moderate solubility in water, which influences its bioavailability and pharmacokinetics. The substance typically appears as a white to off-white crystalline powder. It has a molecular weight of approximately 445.54 g/mol. Glipizide is usually administered in tablet form and is known for its rapid absorption and onset of action, making it effective for controlling postprandial blood glucose levels. Common side effects may include hypoglycemia, weight gain, and gastrointestinal disturbances. As with any medication, it is essential for patients to follow their healthcare provider's guidance regarding dosage and administration to ensure safety and efficacy.
Formula:C21H27N5O4S
InChI:InChI=1S/C21H27N5O4S/c1-15-13-24-19(14-23-15)20(27)22-12-11-16-7-9-18(10-8-16)31(29,30)26-21(28)25-17-5-3-2-4-6-17/h7-10,13-14,17H,2-6,11-12H2,1H3,(H,22,27)(H2,25,26,28)
InChI key:InChIKey=ZJJXGWJIGJFDTL-UHFFFAOYSA-N
SMILES:O=C(NC1CCCCC1)NS(=O)(=O)C2=CC=C(C=C2)CCNC(=O)C3=NC=C(N=C3)C
- Synonyms:
- 1-Cyclohexyl-3-((P-(2-(5-Methylpyrazinecarboxamido)Ethyl)Phenyl)Sulfonyl)Ure
- 2-Pyrazinecarboxamide, N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-5-methyl-
- Aldiab
- Cp 28720
- Digrin
- Dipazide
- Exylurea
- Glibenese
- Glibetin
- Glican
- See more synonyms
- Glidiab
- Glipid
- Glipizibe
- Glipizid
- Glipizida
- Glipizide(Usp)
- Gluco-Rite
- Glucolip
- Glucotrol
- Glucotrol Xl
- GlucotrolXL
- Glucozide
- Glupitel
- Glupizide
- Glyde
- Glydiazinamide
- Glynase
- K 4024
- K4024
- Melizide
- Mindiab
- Minidab
- Minidiab
- Minodiab
- N-(2-(4-(N-(Cyclohexylcarbamoyl)sulfamoyl)phenyl)ethyl)-5-methylpyrazine-2-carboxamide
- N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methylpyrazine-2-carboxamide
- N-(4-[β-(5-Methylpyrazine-2-carboxamido)ethyl]benzenesulfonyl)-N'-cyclohexylurea
- N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-5-methyl-piperazine-2-carboxamide
- N-[2-[4-[[[(Cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-5-methyl-2-pyrazinecarboxamide
- N-[2-[4-[[[(Cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]5-methylpyrazinecarboxamide
- Napizide
- Ozidia
- Pyrazinecarboxamide, N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-5-methyl-
- Samarium(III) ionophore I
- Semiglynase
- Sucrazide
- Tk 1320
- Urea, 1-cyclohexyl-3-[[p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl]sulfonyl]-
