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CAS 29122-68-7

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Atenolol

Description:
Atenolol is a selective beta-1 adrenergic antagonist, primarily used in the treatment of hypertension and certain heart conditions, such as angina and arrhythmias. It is a white to off-white crystalline powder that is soluble in water and has a moderate molecular weight. The chemical formula of atenolol is C14H22N2O3, and it features a hydroxyl group, an ether linkage, and an amine group, contributing to its pharmacological activity. Atenolol works by blocking beta-1 receptors in the heart, leading to decreased heart rate and contractility, which ultimately lowers blood pressure and reduces myocardial oxygen demand. It is typically administered orally and has a relatively long half-life, allowing for once-daily dosing. Atenolol is generally well-tolerated, but potential side effects may include fatigue, dizziness, and bradycardia. As with any medication, it is important for patients to consult healthcare professionals for appropriate use and monitoring.
Formula:C14H22N2O3
InChI:InChI=1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)
InChI key:InChIKey=METKIMKYRPQLGS-UHFFFAOYSA-N
SMILES:O(CC(CNC(C)C)O)C1=CC=C(CC(N)=O)C=C1
Synonyms:
  • (.+-.)-Atenolol
  • (R,S)-Atenolol
  • (RS)-Atenolol
  • 2-(4-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide
  • 2-(4-[2-Hydroxy-3-[(propan-2-yl)amino]propoxy]phenyl)acetamide
  • 2-[4-[2-Hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide
  • 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide
  • <span class="text-smallcaps">DL</span>-Atenolol
  • Acetamide, 2-[p-[2-hydroxy-3-(isopropylamino)propoxy]phenyl]-
  • Alinor
  • See more synonyms
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