CAS 2916433-81-1

Formula: C50H57ClN10O10

InChI: InChI=1S/C50H57ClN10O10/c1-32-45(61(68)69)44(54-71-32)50(67)59-28-26-58(27-29-59)46(34-6-10-36(51)11-7-34)35-8-12-37(13-9-35)70-31-42(63)57-20-16-33(17-21-57)30-56-24-22-55(23-25-56)19-3-18-52-39-5-2-4-38-43(39)49(66)60(48(38)65)40-14-15-41(62)53-47(40)64/h2,4-13,33,40,46,52H,3,14-31H2,1H3,(H,53,62,64)

InChI key: HMSNFNLFZRKDIO-UHFFFAOYSA-N

SMILES: CC1=C(C(=NO1)C(=O)N2CCN(CC2)C(C3=CC=C(C=C3)OCC(=O)N4CCC(CC4)CN5CCN(CC5)CCCNC6=CC=CC7=C6C(=O)N(C7=O)C8CCC(=O)NC8=O)C9=CC=C(C=C9)Cl)[N+](=O)[O-]

4-((3-(4-((1-(2-(4-((4-Chlorophenyl)(4-(5-methyl-4-nitroisoxazole-3-carbonyl)piperazin-1-yl)methyl)phenoxy)acetyl)piperidin-4-yl)methyl)piperazin-1-yl)propyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindol

CAS: 2916433-81-1

4-((3-(4-((1-(2-(4-((4-Chlorophenyl)(4-(5-methyl-4-nitroisoxazole-3-carbonyl)piperazin-1-yl)methyl)phenoxy)acetyl)piperidin-4-yl)methyl)piperazin-1-yl)propyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindol

Formula: C₅₀H₅₇ClN₁₀O₁₀

Purity: 98%

Molecular weight: 993.52

Ref: 54-OR1073877

PROTAC GPX4 degrader-1

CAS: 2916433-81-1

PROTAC GPX4 Degrader-1 (DC-2) is a PROTAC-based compound that efficiently degrades GPX4, demonstrating a degradation concentration (DC 50) of 0.03 μM in HT1080

Formula: C₅₀H₅₇ClN₁₀O₁₀

Color and Shape: Solid

Molecular weight: 993.5

Ref: TM-T74796