CAS 2919213-32-2

Formula: C22H22F2N8O3S

InChI: InChI=1S/C22H22F2N8O3S/c1-25-21(33)13-4-6-15(7-5-13)29-22-28-11-14-10-17(18(23)24)32(19(14)30-22)12-16-20(27-9-8-26-16)31(2)36(3,34)35/h4-11,18H,12H2,1-3H3,(H,25,33)(H,28,29,30)

InChI key: XRVUQRDYWQWGCS-UHFFFAOYSA-N

SMILES: CNC(=O)C1=CC=C(C=C1)NC2=NC=C3C=C(N(C3=N2)CC4=NC=CN=C4N(C)S(=O)(=O)C)C(F)F

FAK-IN-21

CAS: 2919213-32-2

FAK-IN-21 (compound 9) is a FAK inhibitor with an IC₅₀ value of 37.52 nM. It inhibits cell growth and the phosphorylation of FAK, making it useful for research into diffuse gastric cancer.

Formula: C₂₂H₂₂F₂N₈O₃S

Color and Shape: Solid

Molecular weight: 516.52

Ref: TM-T201079