CAS 2920695-77-6

Formula: C33H30F3N5O4

InChI: InChI=1S/C33H30F3N5O4/c1-2-22-24(35)6-5-18-11-21(42)12-23(25(18)22)28-27(36)29-26-30(41-9-4-10-43-15-20(41)16-44-31(26)37-28)39-32(38-29)45-17-33-7-3-8-40(33)14-19(34)13-33/h1,5-6,11-12,19-20,42H,3-4,7-10,13-17H2/t19-,20+,33+/m1/s1

InChI key: LWYZDHJRUISMAW-FSSPWDJASA-N

SMILES: C#CC1=C(C=CC2=CC(=CC(=C21)C3=C(C4=C5C(=NC(=N4)OC[C@@]67CCCN6C[C@@H](C7)F)N8CCCOC[C@H]8COC5=N3)F)O)F

KRAS inhibitor-31

CAS: 2920695-77-6

KRAS inhibitor-31 (compound 33), a potent agent targeting KRAS, exhibits K D (SPR) values of 0.019 nM for KRas G12D, 0.019 nM for KRas G12C, and 0.096 nM for KRas G12V, illustrating its efficacy across these variants.

Formula: C₃₃H₃₀F₃N₅O₄

Color and Shape: Solid

Molecular weight: 617.62

Ref: TM-T200064