CAS 29218-27-7

Toloxatone

Description:

Toloxatone is a chemical compound classified as a monoamine oxidase inhibitor (MAOI), primarily used in the treatment of depression. It is characterized by its ability to inhibit the enzyme monoamine oxidase, which is responsible for the breakdown of neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. By inhibiting this enzyme, toloxatone increases the levels of these neurotransmitters, potentially alleviating depressive symptoms. The compound has a molecular formula that reflects its organic structure, and it is typically administered in a pharmaceutical context. Toloxatone is known for its relatively selective action on the MAO-A isoform, which is significant for its therapeutic effects. However, like other MAOIs, it requires dietary restrictions to avoid hypertensive crises due to interactions with tyramine-rich foods. Its pharmacokinetics, side effects, and interactions with other medications are important considerations in clinical use. Overall, toloxatone represents a specific approach to managing mood disorders through the modulation of neurotransmitter levels in the central nervous system.

Formula: C₁₁H₁₃NO₃

InChI: InChI=1S/C11H13NO3/c1-8-3-2-4-9(5-8)12-6-10(7-13)15-11(12)14/h2-5,10,13H,6-7H2,1H3

InChI key: InChIKey=MXUNKHLAEDCYJL-UHFFFAOYSA-N

SMILES: O=C1N(CC(CO)O1)C2=CC(C)=CC=C2

Synonyms:

• 2-Oxazolidinone, 5-(hydroxymethyl)-3-(3-methylphenyl)-
• 2-Oxazolidinone, 5-hydroxymethyl-3-(m-tolyl)-
• 3-(3-Methylphenyl)-5-hydroxymethyl-2-oxazolidinone
• 5-(Hydroxymethyl)-3-(3-Methylphenyl)-1,3-Oxazolidin-2-One
• 5-(Hydroxymethyl)-3-(3-methylphenyl)-2-oxazolidinone
• 5-Hydroxymethyl-3-(m-tolyl)-2-oxazolidinone
• 69276 Md
• 69276Md
• Brn 0527506
• Delalande 69276
• Humoryl
• Md 69276
• Perenum
• Taloxotone
• Toloxatona
• Toloxatona [INN-Spanish]
• Toloxatone [INN]
• Toloxatonum
• Toloxatonum [INN-Latin]

Toloxatone

CAS: 29218-27-7

Toloxatone

Formula: C₁₁H₁₃NO₃

Purity: 98.5%

Molecular weight: 207.23

Ref: 54-BUP06153

Toloxatone

CAS: 29218-27-7

Formula: C₁₁H₁₃NO₃

Molecular weight: 207.23

Ref: 7W-GP8903

Toloxatone

CAS: 29218-27-7

Formula: C₁₁H₁₃NO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 207.2258

Ref: IN-DA002XQU

Toloxatone

CAS: 29218-27-7

Toloxatone (MD 69276) is a reversible monoamine oxidase A (MAOA) inhibitor.

Formula: C₁₁H₁₃NO₃

Purity: 98.58%

Color and Shape: Solid

Molecular weight: 207.2258

Ref: TM-T5323

5-(Hydroxymethyl)-3-(m-tolyl)oxazolidin-2-one

CAS: 29218-27-7

Formula: C₁₁H₁₃NO₃

Purity: ≥95%

Molecular weight: 207.229

Ref: 10-F324708

Toloxatone

Controlled Product

CAS: 29218-27-7

Applications Toloxatone is a monoamine oxidase-A (MAO-A) inhibitor.
References Goldstein, D. S., et al.: J. Pharmacol. Exp. Ther., 356, 483-492 (2016); Nel, M. S., et al.: Bioorg. Chem., 69, 20-28 (2016)

Formula: C₁₁H₁₃NO₃

Color and Shape: Neat

Molecular weight: 207.226

Ref: TR-T537005