CAS 294-90-6

Cyclen

Description:

Cyclen, or 1,4,7,10-tetraazacyclododecane, is a cyclic polyamine characterized by its unique structure, which consists of a twelve-membered ring containing four nitrogen atoms and eight carbon atoms. This compound is known for its ability to form stable complexes with metal ions, making it valuable in various applications, including coordination chemistry and medicinal chemistry. Cyclen exhibits a high degree of flexibility due to its cyclic nature, which allows it to adapt to different geometries when binding to metal ions. Its nitrogen atoms can act as Lewis bases, facilitating the formation of chelate complexes. Cyclen is also soluble in water and organic solvents, enhancing its utility in biological systems. Additionally, it has been studied for its potential use in drug delivery and as a contrast agent in magnetic resonance imaging (MRI) due to its ability to encapsulate metal ions. Overall, cyclen's unique structural and chemical properties make it a significant compound in both research and practical applications.

Formula: C₈H₂₄N₄

InChI: InChI=1/C8H20N4/c1-2-10-5-6-12-8-7-11-4-3-9-1/h9-12H,1-8H2/p+4

InChI key: InChIKey=QBPPRVHXOZRESW-UHFFFAOYSA-N

SMILES: C1CNCCNCCNCCN1

Synonyms:

• 1,4,7,10-Tetraazacyclododecane
• 1,4,7,10-Tetraazoniacyclododecane
• 1,4,7,10-Tetrazacyclododecane
• Cyclen (1,4,7,10-Tetraazacyclododecane)
• Cyclene
• Gm-D
• NSC 629374
• Tetraaza-12-crown-4

1,4,7,10-Tetraazacyclododecane

CAS: 294-90-6

Formula: C₈H₂₀N₄

Purity: >97.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 172.28

Ref: 3B-T1874

1,4,7,10-Tetraazacyclododecane, min. 98% CYCLEN

CAS: 294-90-6

1,4,7,10-Tetraazacyclododecane, min. 98% CYCLEN

Formula: C₈H₂₀N₄

Purity: min. 98%

Color and Shape: white to off-white pwdr.

Molecular weight: 172.28

Ref: 08-07-1941

1,4,7,10-Tetraazacyclododecane

CAS: 294-90-6

1,4,7,10-Tetraazacyclododecane

Formula: C₈H₂₀N₄

Purity: 97%

Color and Shape: White Solid-Powder

Molecular weight: 172.2712

Ref: 54-OR9089

Cyclen

CAS: 294-90-6

Cyclen

Purity: ≥98%

Molecular weight: 172.27g/mol

Ref: 54-BUP19410

1,4,7,10-Tetraazacyclododecane

CAS: 294-90-6

Formula: C₈H₂₀N₄

Purity: ≥ 97.0%

Color and Shape: White to off-white powder or crystals

Molecular weight: 172.27

Ref: 7W-GE2256

1,4,7,10-Tetraazacyclododecane

CAS: 294-90-6

Formula: C₈H₂₀N₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 172.2712

Ref: IN-DA002Y9W

Cyclen

Controlled Product

CAS: 294-90-6

Applications Macrocyclic aza analogue of the crown ether 12-crown-4. Cyclen compounds are capable of selectively binding cations and are used as a ligand with chemicals used in MRI contrast (as well as other imaging) agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Jeon, J.W. et al.: Bioorg. Med. Chem., 11, 2901 (2003);

Formula: C₈H₂₀N₄

Color and Shape: Neat

Molecular weight: 172.27

Ref: TR-C987745

Gadobutrol Impurity 39 (Cyclen)

CAS: 294-90-6

Formula: C₈H₂₀N₄

Molecular weight: 172.28

Ref: 4Z-G-3148

Cyclen

CAS: 294-90-6

1,4,7,10-Tetraazacyclododecane

Formula: C₈H₂₀N₄

Purity: 98%

Molecular weight: 172.27

Ref: IN-DG33091

Cyclen

CAS: 294-90-6

Cyclen (1,4,7,10-tetraazacyclododecane) is a macrocycle capable of selectively binding cations that used as a ligand in chemistry for instance with chemicals

Formula: C₈H₂₀N₄

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 172.2712

Ref: TM-TJS1183

Cyclen

CAS: 294-90-6

Formula: C₈H₂₀N₄

Molecular weight: 172.27

Ref: BE-RMCG009044

Kryptofix 11 aza

CAS: 294-90-6

Formula: C₈H₂₀N₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 172.169

Ref: 10-F151845

Cyclen

CAS: 294-90-6

Cyclan is an aza-crown ether (analogous to crown-ethers) with a molecular formula (CH2CH2NH)n, where n is 3 to 6. In the case of cyclan, or 1,4,7,10-Tetraazacyclododecane, its structure is formed by 4 units of CH2CH2NH (n=4). In chemical synthesis, the hydrogen atoms of the amine groups in cyclan are substituted by different functional groups to yield a series of modified 1,4,7,10-Tetraazacyclododecane or cyclans, which can be used as chelating agents.

Formula: C₈H₂₀N₄

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 172.27 g/mol

Ref: 3D-FC20678