CAS 29400-42-8

Helvolic acid

Description:

Helvolic acid is a naturally occurring compound classified as a triterpenoid, specifically a type of pentacyclic triterpene. It is primarily derived from certain species of fungi, particularly those in the genus Helvella. This compound is characterized by its complex molecular structure, which includes multiple rings and functional groups that contribute to its biological activity. Helvolic acid exhibits antimicrobial properties, making it of interest in pharmaceutical and agricultural applications. Additionally, it has been studied for its potential anti-inflammatory and anticancer effects. The compound is typically found in a solid state at room temperature and is soluble in organic solvents. Its unique structure and biological activities make helvolic acid a subject of ongoing research in the fields of natural products chemistry and medicinal chemistry. As with many natural compounds, its extraction and purification can be challenging, but advancements in analytical techniques continue to enhance our understanding of its properties and potential uses.

Formula: C₃₃H₄₄O₈

InChI: InChI=1/C33H44O8/c1-17(2)10-9-11-21(30(38)39)26-22-12-13-25-31(6)15-14-23(36)18(3)27(31)28(41-20(5)35)29(37)33(25,8)32(22,7)16-24(26)40-19(4)34/h10,14-15,18,22,24-25,27-28H,9,11-13,16H2,1-8H3,(H,38,39)/b26-21-

InChI key: InChIKey=MDFZYGLOIJNNRM-OAJDADRGSA-N

SMILES: C[C@@]12[C@]3(C)[C@](/C(=C(\CCC=C(C)C)/C(O)=O)/[C@@H](OC(C)=O)C3)(CC[C@]1([C@]4(C)[C@@]([C@H](OC(C)=O)C2=O)([C@H](C)C(=O)C=C4)[H])[H])[H]

Synonyms:

• (2Z)-2-[(17Z)-6,16-bis(acetyloxy)-4,8,10,14-tetramethyl-3,7-dioxogon-1-en-17-ylidene]-6-methylhept-5-enoic acid
• (2Z)-2-[(4alpha,5alpha,6beta,8alpha,9beta,13alpha,14beta,16beta,17Z)-6,16-bis(acetyloxy)-4,8,10,14-tetramethyl-3,7-dioxogon-1-en-17-ylidene]-6-methylhept-5-enoic acid
• (4α,6β,8α,9β,13α,14β,16β,17Z)-6,16-Bis(acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid
• (Z)-6β,16β-Dihydroxy-3,7-dioxo-29-nor-8α,9β,13α,14β-dammara-1,17(20),24-trien-21-oic acid diacetate
• 16-(Acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid
• 29-Nordammara-1,17(20),24-trien-21-oic acid, 6,16-bis(acetyloxy)-3,7-dioxo-, (4-alpha,6-beta,8-alpha,9-beta,13-alpha,14-beta,16-beta,17-beta)-
• 29-Nordammara-1,17(20),24-trien-21-oic acid, 6,16-bis(acetyloxy)-3,7-dioxo-, (4α,6β,8α,9β,13α,14β,16β,17Z)-
• Brn 3230584
• Fumigacin
• Helvolic acid
• Nsc 319943
• 3-10-00-04777 (Beilstein Handbook Reference)
• 6-beta,8-alpha,9-beta,13-alpha,14-beta,16-beta,17-beta)--alph
• Helvolic acid (Fumigacin)
• HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS
• 17(20),24-trien-21-oicacid,6,16-bis(acetyloxy)-3,7-dioxo-29-nordammara-(4
• (8α,9β,13α,14β,17Z)-6β,16β-Diacetoxy-3,7-dioxo-29-nor-5α-dammara-1,17(20),24-trien-21-oic acid
• (8α,9β,13α,14β,17Z)-6β,16β-Bis(acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid

Helvolic acid

CAS: 29400-42-8

Formula: C₃₃H₄₄O₈

Purity: 94.41%

Color and Shape: Whitish. Solid

Molecular weight: 569.0

Ref: 8R-JU0008

Helvolic acid

CAS: 29400-42-8

Helvolic acid

Molecular weight: 568.70g/mol

Ref: 54-BIBR1050

Helvolic acid

CAS: 29400-42-8

Helvolic acid, an antibiotic derived from Xylaria sp., exhibits effectiveness against Gram-positive bacteria.

Formula: C₃₃H₄₄O₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 568.7

Ref: TM-T11551

Helvolic acid

CAS: 29400-42-8

Formula: C₃₃H₄₄O₈

Molecular weight: 568.7

Ref: 7W-GL0753

Helvolic acid

CAS: 29400-42-8

Helvolic acid is a fungal metabolite, which is derived from various species of the Aspergillus and Penicillium genera. It functions as an antifungal antibiotic, disrupting the cell membranes of target fungal cells. This action is primarily attributed to its ability to interfere with sterol synthesis—key components of fungal cell membranes—leading to compromised membrane integrity and subsequent cell death.

Purity: Min. 95%

Ref: 3D-BH162732