CAS 29477-83-6

Narciclasine

Description:

Narciclasine is a naturally occurring alkaloid primarily derived from the plant Narcissus, commonly known as daffodil. It is classified as a member of the Amaryllidaceae family and is known for its complex structure, which includes a fused ring system. This compound exhibits a range of biological activities, including potential anti-cancer properties, as it has been shown to inhibit cell proliferation in various cancer cell lines. Narciclasine interacts with cellular mechanisms, particularly affecting microtubule dynamics, which is crucial for cell division. Additionally, it has been studied for its neuroprotective effects and potential applications in treating neurodegenerative diseases. The compound is characterized by its solubility in organic solvents and relatively low solubility in water, which can influence its bioavailability and pharmacokinetics. As research continues, narciclasine's therapeutic potential and mechanisms of action are being explored, highlighting its significance in medicinal chemistry and pharmacology.

Formula: C₁₄H₁₃NO₇

InChI: InChI=1/C14H13NO7/c16-6-1-5-4-2-7-13(22-3-21-7)11(18)8(4)14(20)15-9(5)12(19)10(6)17/h1-2,6,9-10,12,16-19H,3H2,(H,15,20)/t6-,9+,10+,12-/m0/s1

InChI key: InChIKey=LZAZURSABQIKGB-AEKGRLRDSA-N

SMILES: OC1=C2C(C=3[C@@](NC2=O)([C@H](O)[C@H](O)[C@@H](O)C3)[H])=CC4=C1OCO4

Synonyms:

• (+)-Lycoricidinol
• (+)-Narciclasine
• (2S,3R,4S,4aR)-3,4,4a,5-Tetrahydro-2,3,4,7-tetrahydroxy[1,3]dioxolo[4,5-j]phenanthridin-6(2H)-one
• NSC 266535
• [1,3]Dioxolo[4,5-j]phenanthridin-6(2H)-one, 3,4,4a,5-tetrahydro-2,3,4,7-tetrahydroxy-, [2S-(2α,3β,4β,4aβ)]-
• [1,3]dioxolo[4,5-j]phenanthridin-6(2H)-one, 3,4,4a,5-tetrahydro-2,3,4,7-tetrahydroxy-, (2S,3R,4S,4aR)-
• (2S,3R,4S,4aR)-2,3,4,7-Tetrahydroxy-3,4,4a,5-tetrahydro[1,3]dioxolo[4,5-j]phenanthridin-6(2H)-one
• Lycoricidin-A
• (2S)-3,4,4aβ,5-Tetrahydro-2α,3β,4β,7-tetrahydroxy[1,3]dioxolo[4,5-j]phenanthridin-6(2H)-one
• Narciclasine, 99.9%
• BRN 1087400
• 3,4,4a,5-Tetrahydro-2,3,4,7-tetrahydroxy-(1,3)dioxolo(4,5-j)phenanthridin-6(2H)-one
• (2S-(2-alpha,3-beta,4-beta,4a-beta))-3,4,4a,5-tetrahydro-2,3,4,7-tetrahydroxy-(1,3)Dioxolo(4,5-j)phenanthridin-6(2H)-one
• Narciclasin
• (13β)-1,19-Didehydro-2α,3β,4β,7-tetrahydroxy-11,12-dinor-5,19-secocrinan-6-one
• Lycorcidinol

Narciclasine

CAS: 29477-83-6

Narciclasine

Formula: C₁₄H₁₃NO₇

Purity: ≥98%

Molecular weight: 307.26

Ref: 54-BUP21308

[1,3]Dioxolo[4,5-j]phenanthridin-6(2H)-one, 3,4,4a,5-tetrahydro-2,3,4,7-tetrahydroxy-, (2S,3R,4S,4aR)-

CAS: 29477-83-6

Formula: C₁₄H₁₃NO₇

Purity: 99%

Color and Shape: Solid

Molecular weight: 307.2555

Ref: IN-DA002YIC

Narciclasine

CAS: 29477-83-6

Formula: C₁₄H₁₃NO₇

Purity: 95%~99%

Molecular weight: 307.258

Ref: BP-BP0978

Narciclasine

CAS: 29477-83-6

Formula: C₁₄H₁₃NO₇

Purity: (HPLC) ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 307.26

Ref: 7W-GL5624

Narciclasine

CAS: 29477-83-6

Narciclasine (Lycoricidinol), a natural product, modulates the Rho/Rho-kinase/LIM kinase/cofilin signaling pathway, greatly increasing GTPase RhoA activity.

Formula: C₁₄H₁₃NO₇

Purity: 98.16% - 99.58%

Color and Shape: White Solid

Molecular weight: 307.26

Ref: TM-TQ0183

Narciclasine

CAS: 29477-83-6

Cyclic amide

Formula: C₁₄H₁₃NO₇

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 307.26

Ref: 5G-82604

Narciclasine

CAS: 29477-83-6

Isocarbostyril alkaloid found in the Amaryllidaceae family of flower

Formula: C₁₄H₁₃NO₇

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 307.26 g/mol

Ref: 3D-FT74001

Narciclasine

Controlled Product

CAS: 29477-83-6

Applications Narciclasine is an antiproliferative and pro-apoptotic inducer.

Formula: C₁₄H₁₃NO₇

Color and Shape: Neat

Molecular weight: 307.2555

Ref: TR-N378793