CAS 298-46-4

Carbamazepine

Description:

Carbamazepine is an anticonvulsant and mood-stabilizing drug primarily used in the treatment of epilepsy, bipolar disorder, and neuropathic pain. It is classified as a tricyclic compound and is known for its ability to inhibit voltage-gated sodium channels, thereby stabilizing neuronal membranes and reducing the frequency of seizures. The chemical formula of carbamazepine is C15H12N2O, and it has a molecular weight of approximately 236.26 g/mol. This substance typically appears as a white to off-white crystalline powder and is poorly soluble in water but soluble in organic solvents like ethanol and acetone. Carbamazepine is metabolized in the liver, primarily through cytochrome P450 enzymes, and exhibits a relatively long half-life, necessitating careful monitoring of blood levels in patients. Side effects may include dizziness, drowsiness, and gastrointestinal disturbances, and it can interact with various medications, making it essential for healthcare providers to consider potential drug interactions when prescribing it.

Formula: C₁₅H₁₂N₂O

InChI: InChI=1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18)

InChI key: InChIKey=FFGPTBGBLSHEPO-UHFFFAOYSA-N

SMILES: C(N)(=O)N1C=2C(=CC=CC2)C=CC=3C1=CC=CC3

Synonyms:

• 5-Carbamoyl-5H-Dibenz[B,F]Azepine
• 5H-Dibenz[B,F]Azepine-5-Carboxamide
• 5H-dibenzo[b,f]azepine-5-carboxamide
• Amizepin
• Biston
• CBZ
• Calepsin
• Carbamazepen
• Carbamazepin
• Carbamazepina
• Carbamazepine
• Carbatrol
• Carbazepine
• Carbelan
• Epitol
• Equetro
• Finlepsin
• G 32883
• Geigy 32883
• Karbamazepin
• Karbelex
• Karberol
• Neurotol
• Neurotop
• Nsc 169864
• Sirtal
• Stazepine
• Tegretal
• Tegretol
• Tegretol XR
• Telesmin

Carbamazepin

CAS: 298-46-4

Formula: C₁₅H₁₂N₂O

Purity: >97.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 236.27

Ref: 3B-C1095

Carbamazepine, 98%

CAS: 298-46-4

Carbamazepine is used as cytochrome P450 3A4 inducing anti-epileptic drug and ligand for the GABA-A receptor benzodiazepine modulatory site. Carbamazepine is typically used for the treatment of seizure disorders and neuropathic pain. It is associated with other medications and used to treat schizoph

Formula: C₁₅H₁₂N₂O

Purity: 98%

Color and Shape: White to off-white, Powder

Molecular weight: 236.27

Ref: 02-J62590

Carbamazepine

CAS: 298-46-4

Color and Shape: Neat

Ref: 61-FOR0076.00

Carbamazepine

CAS: 298-46-4

Color and Shape: Neat

Ref: LP-CBM-1732-10

Carbamazepine 1.0 mg/ml in Methanol

CAS: 298-46-4

Color and Shape: Single Solution

Ref: 61-AMP0076.00-01

Carbamazepine, 1mg/ml in Methanol

CAS: 298-46-4

Color and Shape: Single Solution

Ref: LP-CBM-1732-1LM

CARBAMAZEPINE RS

CAS: 298-46-4

CARBAMAZEPINE RS

Ref: 41-ICRS0239

Carbamazepine

CAS: 298-46-4

Carbamazepine

Formula: C₁₅H₁₂N₂O

Purity: 99.9%

Color and Shape: White

Molecular weight: 236.09496

Ref: 47-974

CARBAMAZEPINE CRS

CAS: 298-46-4

CARBAMAZEPINE CRS

Color and Shape: Added Modified

Ref: 41-C0450000

Carbamazepine

CAS: 298-46-4

Anticonvulsants, hypnotics and sedatives

Formula: C₁₅H₁₂N₂O

Color and Shape: White Off-White Solid

Molecular weight: 236.27

Ref: 45-1093001

5H-Dibenz[b,f]azepine-5-carboxamide

CAS: 298-46-4

Formula: C₁₅H₁₂N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 236.2686

Ref: IN-DA00I5IM

Carbamazepine

CAS: 298-46-4

Carbamazepine

Purity: ≥98%

Molecular weight: 236.27g/mol

Ref: 54-BUP16904

Carbamazepine-d4

CAS: 298-46-4

Formula: C₁₅H₈D₄N₂O

Molecular weight: 240.30

Ref: 4Z-C-1946

Carbamazepine (Oxcarbazepine EP Impurity A)

CAS: 298-46-4

Formula: C₁₅H₁₂N₂O

Color and Shape: White To Off-White Solid

Molecular weight: 236.28

Ref: 4Z-C-199

Carbamazepine, USP grade

CAS: 298-46-4

Formula: C₁₅H₁₂N₂O

Purity: ≤ 0.2%

Color and Shape: White to off-white powder

Molecular weight: 236.27

Ref: 7W-GP1918

Carbamazepine

CAS: 298-46-4

Formula: C₁₅H₁₂N₂O

Purity: ≥ 97.0%

Color and Shape: White to off-white powder

Molecular weight: 236.27

Ref: 7W-GP8250

Carbamazepine

CAS: 298-46-4

Carbamazepine

Formula: C₁₅H₁₂N₂O

Purity: By hplc: 99.9% by area (Typical Value in Batch COA)

Color and Shape: white powder

Molecular weight: 236.26858g/mol

Ref: 54-BIC0130

Carbamazepin

Controlled Product

CAS: 298-46-4

Formula: C₁₅H₁₂N₂O

Color and Shape: Neat

Molecular weight: 236.27

Ref: 04-C10968500

Carbamazepine

Controlled Product

CAS: 298-46-4

Formula: C₁₅H₁₂N₂O

Color and Shape: Neat

Molecular weight: 236.27

Ref: 86-MM0076.00

Pharmaceuticals Mixture 326 200 µg/mL in Methanol

Controlled Product

CAS: 103-90-2, 114-07-8, 298-46-4, 56296-78-7, 58-08-2, 723-46-6, 738-70-5, 93107-08-5

Color and Shape: Mixture

Ref: 04-A50000326ME

Carbamazepine

CAS: 298-46-4

Carbamazepine: a tricyclic with anticonvulsant and analgesic effects, treats trigeminal neuralgia.

Formula: C₁₅H₁₂N₂O

Purity: 99.78% - 99.79%

Color and Shape: Solid

Molecular weight: 236.27

Ref: TM-T0943

Carbamazepine

Controlled Product

CAS: 298-46-4

Formula: C₁₅H₁₂N₂O

Color and Shape: Neat

Molecular weight: 236.27

Ref: TR-C175840

Carbamazepine-d2,15N

Controlled Product

CAS: 298-46-4

Formula: C₁₅H₁₀D₂N₁₅NO

Color and Shape: Off White Solid

Molecular weight: 239.27

Ref: TR-C175841

Carbamazepine-d8(Major)

Controlled Product

CAS: 298-46-4

Applications Labelled Carbamazepine (C175840). Used in treatment of pain associated with trigeminal neuralgia. Anticonvulsant.
References Stenger, E.G., et al.: Med. Exp., 11, 191 (1964), Pynnonen, S., et al.: Ther. Drug Monit., 1, 409 (1979), Sidebottom, A., et al.: J. Clin. Pharm. Ther., 20, 31 (1995)

Formula: C₁₅H₄D₈N₂O

Color and Shape: Neat

Molecular weight: 244.32

Ref: TR-C175844

Carbamazepine - Bio-X ™

Controlled Product

CAS: 298-46-4

Carbamazepine is an anticonvulsant that is used to treat epilepsy and nerve pain from trigeminal neuralgia. The mechanism of action for Carbamazepine is not well understood but it is theorized that carbamazepine reduces seizure activity by preventing sodium channel activation. This interaction reduces the frequency and duration of sodium channel opening, slowing down nerve impulses and helping to prevent seizures Studies on animals have shown that carbamazepine works by reducing polysynaptic nerve response and preventing post-tetanic potentiation.

Formula: C₁₅H₁₂N₂O

Purity: (%) Min. 95%

Color and Shape: Powder

Molecular weight: 236.27 g/mol

Ref: 3D-BC166161

Carbamazepine

Controlled Product

CAS: 298-46-4

Carbamazepine is an anticonvulsant epilepsy medication. Carbamazepine binds voltage-gated sodium channels when in their inactive conformation, preventing repetitive and sustained firing. This interaction reduces the frequency and duration of sodium channel opening, slowing down nerve impulses and helping to prevent seizures. As sodium channels are involved in the initiation and propagation of nerve impulses in the brain, they play a key role in the development of seizures. By binding to these channels, carbamazepine stabilizes the electrical activity in the brain and reduces the likelihood of seizures. Carbamazepine is also a GABA agonist as well as having effects on calcium channels and serotonin systems. This leads to further stabilization of the electrical activity in the brain.

Formula: C₁₅H₁₂N₂O

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 236.27 g/mol

Ref: 3D-FC19679

5H-Dibenzo[b,f]azepine-5-carboxamide

CAS: 298-46-4

Formula: C₁₅H₁₂N₂O

Purity: 98%

Color and Shape: White powder

Molecular weight: 236.274

Ref: 10-F242225

Oxcarbazepine EP Impurity A

CAS: 298-46-4

Formula: C₁₅H₁₂N₂O

Molecular weight: 236.3

Ref: ST-EA-CP-O13001