CAS 298-57-7

Cinnarizine

Description:

Cinnarizine is a chemical compound classified as a piperazine derivative and is primarily used as an antihistamine and antiemetic. Its chemical formula is C26H28N2, and it features a complex structure that includes a diphenylmethyl group and a piperazine ring. Cinnarizine is known for its ability to inhibit calcium channels, which contributes to its effectiveness in treating motion sickness and vertigo. It exhibits moderate lipophilicity, allowing it to cross the blood-brain barrier, which is significant for its central nervous system effects. The compound is typically administered in oral form and is well-absorbed in the gastrointestinal tract. Cinnarizine may cause side effects such as drowsiness, dry mouth, and gastrointestinal disturbances. It is important to note that while it is effective for certain conditions, its use should be monitored due to potential interactions with other medications and its sedative properties. Overall, cinnarizine is a valuable therapeutic agent in the management of vestibular disorders and motion-related ailments.

Formula: C₂₆H₂₈N₂

InChI: InChI=1/C26H28N2/c1-4-11-23(12-5-1)13-10-18-27-19-21-28(22-20-27)26(24-14-6-2-7-15-24)25-16-8-3-9-17-25/h1-12,14-18,26H,13,19-22H2/b18-10+

InChI key: InChIKey=DERZBLKQOCDDDZ-UHFFFAOYSA-N

SMILES: C(N1CCN(CC=CC2=CC=CC=C2)CC1)(C3=CC=CC=C3)C4=CC=CC=C4

Synonyms:

• 1-(3-Phenylallyl)-4-(diphenylmethyl)piperazine
• 1-(Diphenylmethyl)-4-(3-phenyl-2-propen-1-yl)piperazine
• 1-(Diphenylmethyl)-4-(3-phenyl-2-propenyl)piperazine
• 1-(diphenylmethyl)-4-[(1E)-3-phenylprop-1-en-1-yl]piperazine
• 1-Benzhydryl-4-Trans-Cinnamylpiperazine
• 1-Benzhydryl-4-cinnamylpiperazine
• 1-Cinnamyl-4-(diphenylmethyl)piperazine
• 1-Cinnamyl-4-benzhydrylpiperazine
• 1-Cynnamyl-4-diphenylmethylpiperazine
• 1-Diphenylmethyl-4-cinnamoylpiperazine
• 516 Md
• 516Md
• Aplactan
• Aplexal
• Apotomin
• Artate
• Carecin
• Cerebolan
• Cerepar
• Cinaperazine
• Cinarizina
• Cinarizine
• Cinazyn
• Cinnacet
• Cinnageron
• Cinnarazine
• Cinnarizin
• Cinnarizinum
• Cinnipirine
• Corathiem
• Denapol
• Dimitron
• Dimitronal
• Eglen
• Folcodal
• Giganten
• Glanil
• Hilactan
• Ixterol
• Katoseran
• Labyrin
• Lazeta
• Marisan
• Midronal
• Mitronal
• N-Benzhydryl-N'-cinnamylpiperazine
• Olamin
• Piperazine, 1-(diphenylmethyl)-4-(3-phenyl-2-propen-1-yl)-
• Piperazine, 1-(diphenylmethyl)-4-(3-phenyl-2-propenyl)-
• Piperazine, 1-cinnamyl-4-(diphenylmethyl)-
• Processine
• R 1575
• R 516
• Sedatromin
• Sepan
• Siptazin
• Spaderizine
• Stugeron
• Stunarone
• Stutgeron
• Stutgin
• Toliman
• Vergo
• (E)-1-(DIPHENYLMETHYL)-4-(3-PHENYL PROP-2-ENYL) PIPERAZINE
• LABOTEST-BB LT00134701
• 1-(diphenylmethyl)-4-(3-phenyl-2-propenyl)-piperazin
• 1-Cinnamyl-4-diphenylmethylpiperazine
• CINNARIZINE
• 1-TRANS-CINNAMYL-4-DIPHENYLMETHYLPIPERAZINE
• 1-cinnamyl-4-(diphenylmethyl)-piperazin

Cinnarizine

CAS: 298-57-7

Formula: C₂₆H₂₈N₂

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 368.52

Ref: 3B-C3459

Cinnarizine

CAS: 298-57-7

An antihistamine

Formula: C₂₆H₂₈N₂

Color and Shape: White to cream, powder

Molecular weight: 368.52

Ref: 02-J64568

Cinnarizine

CAS: 298-57-7

Color and Shape: Neat

Ref: 61-FOR1038.00

Cinnarizine

CAS: 298-57-7

Cinnarizine

Formula: C₂₆H₂₈N₂

Purity: 100.0%

Color and Shape: Off-White

Molecular weight: 368.22525

Ref: 47-1219

CINNARIZINE CRS

CAS: 298-57-7

CINNARIZINE CRS

Formula: C₂₆H₂₈N₂

Molecular weight: 368.5139

Ref: 41-C2180000

Cinnarizine

CAS: 298-57-7

Cinnarizine is a piperazine, blocks H1-receptor & Ca-channels, has vasodilating & antiemetic effects, may cause Parkinson-like symptoms.

Formula: C₂₆H₂₈N₂

Purity: 99.94%

Color and Shape: Solid

Molecular weight: 368.51

Ref: TM-T0903

Cinnarizine

CAS: 298-57-7

Cinnarizine

Purity: ≥98%

Molecular weight: 368.51g/mol

Ref: 54-BUP14772

1-Benzhydryl-4-Cinnamylpiperazine

CAS: 298-57-7

1-Benzhydryl-4-Cinnamylpiperazine

Purity: 99%

Molecular weight: 368.51g/mol

Ref: 54-OR1009362

Cinnarizine

CAS: 298-57-7

Formula: C₂₆H₂₈N₂

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 368.52

Ref: 7W-GP9214

Cinnarizine

CAS: 298-57-7

Formula: C₂₆H₂₈N₂

Color and Shape: Off-White Solid

Molecular weight: 368.52

Ref: 4Z-C-381

Cinnarizine-d8

CAS: 298-57-7

Formula: C₂₆H₂₀D₈N₂

Color and Shape: Off-White Solid

Molecular weight: 376.57

Ref: 4Z-C-382

Cinnarizine

CAS: 298-57-7

Formula: C₂₆H₂₈N₂

Color and Shape: Neat

Molecular weight: 368.51

Ref: 86-MM1038.00

Cinnarizine

CAS: 298-57-7

Formula: C₂₆H₂₈N₂

Color and Shape: Neat

Molecular weight: 368.51

Ref: 04-C11666465

Cinnarizine

CAS: 298-57-7

Applications Calcium channel blocker with antiallergic and anti-vasoconstricting activity. Antihistaminic.
References Barber, J.H., et al.: Pharmatherapeutica, 2, 401 (1980), Spedding, M., et al.: Arch. Pharmacol., 318, 234 (1982), Morad, et al.: Pharmacol. Res., 35, 177 (1997)

Formula: C₂₆H₂₈N₂

Color and Shape: Neat

Molecular weight: 368.51

Ref: TR-C465300

Cinnarizine - Bio-X ™

CAS: 298-57-7

Cinnarizine is calcium channel blocker that is used for the treatment of symptoms associated with labyrinthine disorder such as vertigo, nausea, tinnitus and vomiting. This drug can also be viewed as a nootropic drug because of its vasorelaxating abilities. It inhibits contractions of vascular smooth muscle cells by blocking L-type voltage gated calcium channels.

Formula: C₂₆H₂₈N₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 368.51 g/mol

Ref: 3D-BC167081

1-trans-Cinnamyl-4-diphenylmethylpiperazine

CAS: 298-57-7

Calcium channel blocker; piperazine derivative

Formula: C₂₆H₂₈N₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 368.51 g/mol

Ref: 3D-FC20452

CINNARIZINE

CAS: 298-57-7

Purity: 99%

Molecular weight: 368.5239868

Ref: 10-F814438

Cinnarizine Glucuronide

Controlled Product

CAS: 298-57-7

Formula: C₃₂H₃₇N₂O₆

Color and Shape: Neat

Molecular weight: 545.646

Ref: TR-C465350

Cinnarizine-d8 Glucuronide

Controlled Product

CAS: 298-57-7

Formula: C₃₂D₈H₂₉N₂O₆

Color and Shape: Neat

Molecular weight: 553.695

Ref: TR-C465352