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CAS 298-57-7

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Cinnarizine

Description:
Cinnarizine is a chemical compound classified as a piperazine derivative and is primarily used as an antihistamine and antiemetic. Its chemical formula is C26H28N2, and it features a complex structure that includes a diphenylmethyl group and a piperazine ring. Cinnarizine is known for its ability to inhibit calcium channels, which contributes to its effectiveness in treating motion sickness and vertigo. It exhibits moderate lipophilicity, allowing it to cross the blood-brain barrier, which is significant for its central nervous system effects. The compound is typically administered in oral form and is well-absorbed in the gastrointestinal tract. Cinnarizine may cause side effects such as drowsiness, dry mouth, and gastrointestinal disturbances. It is important to note that while it is effective for certain conditions, its use should be monitored due to potential interactions with other medications and its sedative properties. Overall, cinnarizine is a valuable therapeutic agent in the management of vestibular disorders and motion-related ailments.
Formula:C26H28N2
InChI:InChI=1/C26H28N2/c1-4-11-23(12-5-1)13-10-18-27-19-21-28(22-20-27)26(24-14-6-2-7-15-24)25-16-8-3-9-17-25/h1-12,14-18,26H,13,19-22H2/b18-10+
InChI key:InChIKey=DERZBLKQOCDDDZ-UHFFFAOYSA-N
SMILES:C(N1CCN(CC=CC2=CC=CC=C2)CC1)(C3=CC=CC=C3)C4=CC=CC=C4
Synonyms:
  • 1-(3-Phenylallyl)-4-(diphenylmethyl)piperazine
  • 1-(Diphenylmethyl)-4-(3-phenyl-2-propen-1-yl)piperazine
  • 1-(Diphenylmethyl)-4-(3-phenyl-2-propenyl)piperazine
  • 1-(diphenylmethyl)-4-[(1E)-3-phenylprop-1-en-1-yl]piperazine
  • 1-Benzhydryl-4-Trans-Cinnamylpiperazine
  • 1-Benzhydryl-4-cinnamylpiperazine
  • 1-Cinnamyl-4-(diphenylmethyl)piperazine
  • 1-Cinnamyl-4-benzhydrylpiperazine
  • 1-Cynnamyl-4-diphenylmethylpiperazine
  • 1-Diphenylmethyl-4-cinnamoylpiperazine
  • See more synonyms
products per page.Found 24 products.
  • CINNARIZINE

    CAS:
    Purity:98%
    Molecular weight:368.5239868

    Ref: 10-F814438

    1g
    17.00€
    5g
    40.00€
    25g
    110.00€
  • Cinnarizine-d8 Glucuronide

    Controlled Product
    CAS:
    Formula:C32D8H29N2O6
    Color and Shape:Neat
    Molecular weight:553.695

    Ref: TR-C465352

    75mg
    17,982.00€
  • Cinnarizine Glucuronide

    Controlled Product
    CAS:
    Formula:C32H37N2O6
    Color and Shape:Neat
    Molecular weight:545.646

    Ref: TR-C465350

    100mg
    9,732.00€
  • Cinnarizine

    CAS:
    Formula:C26H28N2
    Molecular weight:368.52

    Ref: ST-EA-CP-C76000

    10mg
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    25mg
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    50mg
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    100mg
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