CAS 298-59-9

Ritalin

Description:

Ritalin, chemically known as methylphenidate, is a central nervous system stimulant primarily used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. It is classified as a piperidine derivative and has a molecular formula of C14H19NO2. Methylphenidate acts by inhibiting the reuptake of dopamine and norepinephrine in the brain, thereby enhancing focus and attention. The substance is typically administered in various formulations, including immediate-release and extended-release tablets. Ritalin is known for its potential side effects, which can include insomnia, decreased appetite, and increased heart rate. It is classified as a Schedule II controlled substance in many jurisdictions due to its potential for abuse and dependence. The compound is usually well-absorbed when taken orally, with peak plasma concentrations occurring within a few hours. Its pharmacokinetics can vary based on the formulation, influencing the duration of action and therapeutic effects. Overall, Ritalin is a widely studied and utilized medication in the management of ADHD symptoms.

Formula: C₁₄H₁₉NO₂·ClH

InChI: InChI=1S/C14H19NO2.ClH/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12;/h2-4,7-8,12-13,15H,5-6,9-10H2,1H3;1H

InChI key: InChIKey=JUMYIBMBTDDLNG-UHFFFAOYSA-N

SMILES: C(C(OC)=O)(C1=CC=CC=C1)C2CCCCN2.Cl

Synonyms:

• 2-Piperidineacetic acid, α-phenyl-, methyl ester, hydrochloride
• 2-Piperidineacetic acid, α-phenyl-, methyl ester, hydrochloride (1:1)
• Centedrin
• Centedrine
• Concerta
• Medikinet
• Meridil
• Metadate CD
• Methyl Phenyl(Piperidin-2-Yl)Acetate Hydrochloride (1:1)
• Methyl α-phenyl-2-piperidineacetate hydrochloride
• Methylphenidate HCl
• Methylphenidate Hydrochloride
• NSC 169868
• Quillivant XR
• Ritalin
• Ritalin Hydrochloride
• Ritalin LA
• Ritalin SR

d,l-Methylphenidate.HCl

Controlled Product

CAS: 298-59-9

Color and Shape: Neat

Ref: LP-MPH-1043-HC-10

d,l-Methylphenidate.HCl, 1mg/ml in Methanol (as free base)

Controlled Product

CAS: 298-59-9

Color and Shape: Single Solution

Ref: LP-MPH-1043-HC-1LM

Methylphenidate Hydrochloride

Controlled Product

CAS: 298-59-9

Applications Controlled substance (stimulant). CNS stimulant. Four isomers of Methylphenidate are known to exist. One pair of threo isomers and one pair of erythro are distinguished, from which only d-threo-Methylphenidate exhibits the pharmacologically usually desired effects. This compound is a 4:1 mixture of rac-erythro (M325670) and rac-threo (M325671).
References Greenblatt, E.N., et al.: J. Pharmacol. Exp. Ther., 131, 115 (1961), Padmanabhan, G.R., Anal. Profiles Drug Subs., 10, 473 (1981), Srinivas, N.R., et al.: Pharm. Res., 10, 14 (1993),

Formula: C₁₄H₁₉NO₂·ClH

Color and Shape: White To Off-White

Molecular weight: 269.77

Ref: TR-M325880

DL-Methylphenidate hydrochloride

Controlled Product

CAS: 298-59-9

Methylphenidate is a psychostimulant drug that is used in the treatment of attention deficit/hyperactivity disorder (ADHD) and narcolepsy. It is a central nervous system stimulant that affects dopamine and norepinephrine levels in the brain. Methylphenidate blocks reuptake of these neurotransmitters, which increases their availability to nerve cells, therefore increasing their activity. When administered orally, methylphenidate reaches peak plasma concentrations within 3-5 hours. The half-life of methylphenidate ranges from 11-18 hours depending on dosage form, with time to maximum concentration ranging from 1-2 hours. The major metabolites of methylphenidate are ritalinic acid and pemoline; both are inactive. Methylphenidate is contraindicated in individuals with a history of addiction, psychosis or bipolar disorder.

Formula: C₁₄H₁₉NO₂·HCl

Purity: 98.0 To 102.0%

Color and Shape: Powder

Molecular weight: 269.77 g/mol

Ref: 3D-FM35271

Methylphenidate hydrochloride

Controlled Product

CAS: 298-59-9

Methylphenidate hydrochloride

Formula: C₁₄H₁₉NO₂HCl

Purity: 99.8%

Color and Shape: White

Molecular weight: 269.11826

Ref: 47-1201

Methylphenidate Hydrochloride (1 mg/mL in Methanol)

Controlled Product

CAS: 298-59-9

Formula: C₁₄H₁₉NO₂·ClH

Color and Shape: Colourless

Molecular weight: 269.77

Ref: TR-KIT0450