CAS 298-93-1

[3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide]

Description:

[3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide], commonly known as MTT, is a yellow, water-soluble compound widely used in cell viability assays. Its chemical structure features a tetrazolium ring, which is crucial for its function as a colorimetric reagent. Upon reduction by viable cells, MTT is converted into a purple formazan product, allowing for quantification of cell metabolic activity. MTT is stable under normal conditions but should be stored in a cool, dark place to prevent degradation. It is soluble in aqueous solutions at physiological pH, making it suitable for biological applications. The compound is non-toxic to cells at low concentrations, which is essential for accurate viability assessments. MTT assays are commonly employed in pharmacology and toxicology to evaluate the effects of drugs and other substances on cell health. However, care must be taken when interpreting results, as factors such as cell type and assay conditions can influence outcomes. Overall, MTT is a valuable tool in research for assessing cellular health and proliferation.

Formula: C₁₈H₁₆N₅S·Br

InChI: InChI=1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1

InChI key: InChIKey=AZKSAVLVSZKNRD-UHFFFAOYSA-M

SMILES: CC=1N=C(N2[N+](=NC(=N2)C3=CC=CC=C3)C4=CC=CC=C4)SC1C.[Br-]

Synonyms:

• 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide
• Thiazolyl Blue
• 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide
• Thiazolyl Blue tetrazolium bromide
• Mtt (1.11714)
• 3-(4,5-dimethyl-1,3-thiazol-2-yl)-2,5-diphenyl-2,3-dihydro-1H-tetrazol-1-ium bromide
• 3-(4,5-Dimethyl-2-thizolyl)-2,5-diphenyltertazolium bromide
• 3-(4,5-Dimethyl-2-THIAZOL-2-YL)-2,5-DIPHENYL-2H-TETRAZOLIUM BROMIDE
• 3-(4,5-Dimethyl-2-THIAZOLYL)-2,5-DIPHENYLTETRAZOLIUM BROMIDE
• 3-(4,5-Dimethylithiazolyl-2)-2,5-Diphenyl Monotetrazolium Bromide
• 3,[4,5-Dimethylthiazol-2-YL]-2,5-DIPHENYLTETRAZOLIUM BROMIDE
• 3-(4,5-Dimethylthiazol-2-YL)-2,5-DIPHYL-2 H-TETRAZOLIUM BROMIDE
• 3-(4,5-Dimethylthiazolyl-2)-2,5-DIPHENYL TETRAZOLIUM BROMIDE
• Methylthiazoletetrazolium
• 3-(4,5-Dimethylthiazol-2-Yl)-2,5-Diphenyl-2H-Tetrazoliumbromide
• 3-(4,5-dimethyl-1,3-thiazol-2-yl)-2,5-diphenyl-2H-tetrazol-3-ium bromide
• 4,5-Dimethythiazoyl-Zyl2,5-Diphenylterrajolium Bromiole
• 2-(4,5-Dimethylthiazol-2-yl)-3,5-diphenyl-2H-tetrazolium bromide
• 2,5-Diphenyl-3-(4,5-dimethylthiazol-2-yl)-2H-tetrazolium bromide
• 2,5-Diphenyl-3-(4,5-dimethylthiazol-2-yl)tetrazolium bromide
• 2H-Tetrazolium, 2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-, bromide
• 2H-Tetrazolium, 2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-, bromide (1:1)
• 3-(4',5'-Dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium bromide
• 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromid
• 3-(4,5-Dimethylthiazolyl)-2,5-diphenyl-2H-tetrazolium bromide
• 3-(4,5-Dimethylthiazolyl)-2,5-diphenyltetrazolium bromide
• Bromure de 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium
• Bromure De 3-(4,5-Dimethylthiazole-2-Yl)-2,5-Diphenyltetrazolium
• Bromuro De 3-(4,5-Dimetiltiazol-2-Il)-2,5-Difeniltetrazolio
• MMT Tetrazolium
• MTT tetrazolium
• Nsc 60102
• Thiazolyl blue (Sigma)
• Thiazolyl Blue Monotetrazolium

3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium Bromide

CAS: 2348-71-2, 298-93-1

Formula: C₁₈H₁₆BrN₅S

Purity: >98.0%(T)

Color and Shape: Light yellow to Brown powder to crystal

Molecular weight: 414.33

Ref: 3B-D0801

Thiazolyl Blue tetrazolium bromide, 98%

CAS: 298-93-1

Used in measurement of cell proliferation. Produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.Thiazolyl Blue tetrazolium bromide is a dye used in measurement of cell proliferation. It is used as a direct indicato

Formula: C₁₈H₁₆BrN₅S

Purity: 98%

Color and Shape: Crystals or powder or crystalline powder, White to yellow

Molecular weight: 414.33

Ref: 02-L11939

3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2,3-dihydro-1H-tetrazol-3-ium bromide

CAS: 298-93-1

Formula: C₁₈H₁₆BrN₅S

Purity: 95%

Color and Shape: Solid

Molecular weight: 414.3221

Ref: IN-DA003URZ

Thiazolyl Blue

CAS: 298-93-1

Thiazolyl Blue

Purity: ≥98%

Molecular weight: 414.32g/mol

Ref: 54-BUP19260

Thiazolyl blue tetrazolium bromide

CAS: 298-93-1

Formula: C₁₈H₁₆BrN₅S

Purity: ≥ 98.0%

Color and Shape: Pale yellow to yellow crystalline powder

Molecular weight: 414.33

Ref: 7W-GC4568

3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide

CAS: 298-93-1

3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide

Formula: C₁₈H₁₆N₅S·Br

Purity: 95%

Color and Shape: yellow solid

Molecular weight: 414.32214g/mol

Ref: 54-BID2165

MTT [for Biochemical Research]

CAS: 298-93-1

Formula: C₁₈H₁₆BrN₅S

Purity: >97.0%(HPLC)

Color and Shape: Light yellow to Brown powder to crystal

Molecular weight: 414.33

Ref: 3B-M3297

Thiazolyl Blue

CAS: 298-93-1

Thiazolyl Blue (MTT) is a colorimetric compound widely used in measuring cell proliferation. It is reduced from yellow color to purple formazan in living cells.

Formula: C₁₈H₁₆BrN₅S

Purity: 98.73% - 99.65%

Color and Shape: Yellow Powder Yellowish Orange Crystalline Powder

Molecular weight: 414.32

Ref: TM-T19029

2-(4,5-Dimethylthiazol-2-yl)-3,5-diphenyl-2H-tetrazol-3-ium bromide

CAS: 298-93-1

Purity: 95%

Molecular weight: 414.3299865722656

Ref: 10-F868291

MTT

CAS: 298-93-1

Applications MTT (cas# 298-93-1) is a useful research chemical. Dyes and metabolites.

Formula: C₁₈H₁₆N₅SBr

Color and Shape: Neat

Molecular weight: 414.32

Ref: TR-M760505

Methylthiazolyldiphenyl-tetrazolium bromide

CAS: 298-93-1

Purity: 98.0%

Color and Shape: Solid

Molecular weight: 414.3299865722656

Ref: 10-F047891

Thiazolyl blue tetrazolium bromide

CAS: 298-93-1

Thiazolyl blue tetrazolium bromide, also called 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide and methylthiazolyldiphenyl-tetrazolium bromide, and mainly known as MTT, is employed in the so-called MTT reduction or colorimetric assay. The MTT assay is used to determine the metabolic activity of living cells and the viable cell number in proliferation and cytotoxicity studies. The assay is based on the enzymatic reduction of the yellow MTT to the purple-blue water-insoluble formazan catalysed by mitochondrial dehydrogenases of living cells. The amount of formazan produced is directly proportional to the number of viable cells and can be quantified by measuring absorbance at 570nm. The MTT assay is broadly employed in cell biology because it is rapid and economical. MTT is also used as enzyme substrates in studies of nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.

Formula: C₁₈H₁₆BrN₅S

Purity: Min. 97 Area-%

Color and Shape: Yellow Powder

Molecular weight: 414.32 g/mol

Ref: 3D-ET15853

Thiazolyl Blue Tetrazolium Bromide (MTT) for tissue culture, 98%

CAS: 298-93-1

Formula: C₁₈H₁₆N₅SBr

Purity: min. 98%

Color and Shape: Yellow, Crystalline powder, Clear, Yellow

Molecular weight: 414.32

Ref: SR-58945

Thiazolyl Blue Tetrazolium Bromide (MTT) extrapure AR, 98%

CAS: 298-93-1

Formula: C₁₈H₁₆N₅SBr

Purity: min. 98%

Color and Shape: Yellow, Crystalline powder, Clear, Yellow

Molecular weight: 414.32

Ref: SR-33611

Thiazolyl Blue Tetrazolium Bromide

CAS: 298-93-1

Thiazolyl blue tetrazolium bromide, also called 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide and methylthiazolyldiphenyl-tetrazolium bromide, and mainly known as MTT, is employed in the so-called MTT reduction or colorimetric assay. The MTT assay is used to determine the metabolic activity of living cells and the viable cell number in proliferation and cytotoxicity studies. The assay is based on the enzymatic reduction of the yellow MTT to the purple-blue water-insoluble formazan catalysed by mitochondrial dehydrogenases of living cells. The amount of formazan produced is directly proportional to the number of viable cells and can be quantified by measuring absorbance at 570nm. The MTT assay is broadly employed in cell biology because it is rapid and economical. MTT is also used as enzyme substrates in studies of nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.

Formula: C₁₈H₁₆BrN₅S

Purity: Min. 95.0 Area-%

Molecular weight: 414.32 g/mol

Ref: 3D-T-3450