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CAS 298-93-1
:[3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide]
Description:
[3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide], commonly known as MTT, is a yellow, water-soluble compound widely used in cell viability assays. Its chemical structure features a tetrazolium ring, which is crucial for its function as a colorimetric reagent. Upon reduction by viable cells, MTT is converted into a purple formazan product, allowing for quantification of cell metabolic activity. MTT is stable under normal conditions but should be stored in a cool, dark place to prevent degradation. It is soluble in aqueous solutions at physiological pH, making it suitable for biological applications. The compound is non-toxic to cells at low concentrations, which is essential for accurate viability assessments. MTT assays are commonly employed in pharmacology and toxicology to evaluate the effects of drugs and other substances on cell health. However, care must be taken when interpreting results, as factors such as cell type and assay conditions can influence outcomes. Overall, MTT is a valuable tool in research for assessing cellular health and proliferation.
Formula:C18H16N5S·Br
InChI:InChI=1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1
InChI key:InChIKey=AZKSAVLVSZKNRD-UHFFFAOYSA-M
SMILES:CC=1N=C(N2[N+](=NC(=N2)C3=CC=CC=C3)C4=CC=CC=C4)SC1C.[Br-]
Synonyms:- 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide
- Thiazolyl Blue
- 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide
- Thiazolyl Blue tetrazolium bromide
- Mtt (1.11714)
- 3-(4,5-dimethyl-1,3-thiazol-2-yl)-2,5-diphenyl-2,3-dihydro-1H-tetrazol-1-ium bromide
- 3-(4,5-Dimethyl-2-thizolyl)-2,5-diphenyltertazolium bromide
- 3-(4,5-Dimethyl-2-THIAZOL-2-YL)-2,5-DIPHENYL-2H-TETRAZOLIUM BROMIDE
- 3-(4,5-Dimethyl-2-THIAZOLYL)-2,5-DIPHENYLTETRAZOLIUM BROMIDE
- 3-(4,5-Dimethylithiazolyl-2)-2,5-Diphenyl Monotetrazolium Bromide
- 3,[4,5-Dimethylthiazol-2-YL]-2,5-DIPHENYLTETRAZOLIUM BROMIDE
- 3-(4,5-Dimethylthiazol-2-YL)-2,5-DIPHYL-2 H-TETRAZOLIUM BROMIDE
- 3-(4,5-Dimethylthiazolyl-2)-2,5-DIPHENYL TETRAZOLIUM BROMIDE
- Methylthiazoletetrazolium
- 3-(4,5-Dimethylthiazol-2-Yl)-2,5-Diphenyl-2H-Tetrazoliumbromide
- 3-(4,5-dimethyl-1,3-thiazol-2-yl)-2,5-diphenyl-2H-tetrazol-3-ium bromide
- 4,5-Dimethythiazoyl-Zyl2,5-Diphenylterrajolium Bromiole
- 2-(4,5-Dimethylthiazol-2-yl)-3,5-diphenyl-2H-tetrazolium bromide
- 2,5-Diphenyl-3-(4,5-dimethylthiazol-2-yl)-2H-tetrazolium bromide
- 2,5-Diphenyl-3-(4,5-dimethylthiazol-2-yl)tetrazolium bromide
- 2H-Tetrazolium, 2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-, bromide
- 2H-Tetrazolium, 2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-, bromide (1:1)
- 3-(4',5'-Dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium bromide
- 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromid
- 3-(4,5-Dimethylthiazolyl)-2,5-diphenyl-2H-tetrazolium bromide
- 3-(4,5-Dimethylthiazolyl)-2,5-diphenyltetrazolium bromide
- Bromure de 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium
- Bromure De 3-(4,5-Dimethylthiazole-2-Yl)-2,5-Diphenyltetrazolium
- Bromuro De 3-(4,5-Dimetiltiazol-2-Il)-2,5-Difeniltetrazolio
- MMT Tetrazolium
- MTT tetrazolium
- Nsc 60102
- Thiazolyl blue (Sigma)
- Thiazolyl Blue Monotetrazolium
- See more synonyms
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3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium Bromide
CAS:Formula:C18H16BrN5SPurity:>98.0%(T)Color and Shape:Light yellow to Brown powder to crystalMolecular weight:414.33MTT [for Biochemical Research]
CAS:Formula:C18H16BrN5SPurity:>97.0%(HPLC)Color and Shape:Light yellow to Brown powder to crystalMolecular weight:414.33Thiazolyl Blue tetrazolium bromide, 98%
CAS:Used in measurement of cell proliferation. Produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.Thiazolyl Blue tetrazolium bromide is a dye used in measurement of cell proliferation. It is used as a direct indicatoFormula:C18H16BrN5SPurity:98%Color and Shape:Crystals or powder or crystalline powder, White to yellowMolecular weight:414.333-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide
CAS:3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromideFormula:C18H16N5S·BrPurity:95%Color and Shape:SolidMolecular weight:414.32214Thiazolyl Blue, 10mM (in DMSO)
CAS:Thiazolyl Blue, 10mM (in DMSO)Formula:C18H16BrN5SPurity:≥98%, 10 mM in DMSOColor and Shape:SolidMolecular weight:414.32Thiazolyl blue tetrazolium bromide
CAS:Formula:C18H16BrN5SPurity:≥ 98.0%Color and Shape:Pale yellow to yellow crystalline powderMolecular weight:414.333-(4,5-Dimethylthiazolyl)-2,5-diphenyl-2H-tetrazolium bromide
CAS:Formula:C18H16BrN5SPurity:95%Color and Shape:SolidMolecular weight:414.3221MTT
CAS:Applications MTT (cas# 298-93-1) is a useful research chemical. Dyes and metabolites.
Formula:C18H16N5SBrColor and Shape:NeatMolecular weight:414.32Thiazolyl Blue
CAS:2-(4,5-Dimethylthiazol-2-yl)-3,5-diphenyl-2H-tetrazol-3-ium bromideFormula:C18H16BrN5SPurity:98%Molecular weight:414.32Thiazolyl Blue
CAS:Thiazolyl Blue (MTT) is a colorimetric compound widely used in measuring cell proliferation. It is reduced from yellow color to purple formazan in living cells.Formula:C18H16BrN5SPurity:98.73% - 99.91%Color and Shape:Yellow SolidMolecular weight:414.3222-(4,5-Dimethylthiazol-2-yl)-3,5-diphenyl-2H-tetrazol-3-ium bromide
CAS:Purity:95%Molecular weight:414.3299865722656Thiazolyl blue tetrazolium bromide
CAS:Thiazolyl blue tetrazolium bromide, also called 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide and methylthiazolyldiphenyl-tetrazolium bromide, and mainly known as MTT, is employed in the so-called MTT reduction or colorimetric assay. The MTT assay is used to determine the metabolic activity of living cells and the viable cell number in proliferation and cytotoxicity studies. The assay is based on the enzymatic reduction of the yellow MTT to the purple-blue water-insoluble formazan catalysed by mitochondrial dehydrogenases of living cells. The amount of formazan produced is directly proportional to the number of viable cells and can be quantified by measuring absorbance at 570nm. The MTT assay is broadly employed in cell biology because it is rapid and economical. MTT is also used as enzyme substrates in studies of nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.
Formula:C18H16BrN5SPurity:Min. 97 Area-%Color and Shape:Yellow PowderMolecular weight:414.32 g/molMethylthiazolyldiphenyl-tetrazolium bromide
CAS:Formula:C18H16BrN5SPurity:95%Color and Shape:SolidMolecular weight:413.031Thiazolyl Blue
CAS:2-(4,5-Dimethylthiazol-2-yl)-3,5-diphenyl-2H-tetrazol-3-ium bromideFormula:C18H16BrN5SPurity:95%Molecular weight:414.32Thiazolyl Blue Tetrazolium Bromide (MTT) extrapure AR, 98%
CAS:Formula:C18H16N5SBrPurity:min. 98%Color and Shape:Yellow, Crystalline powder, Clear, YellowMolecular weight:414.32Thiazolyl Blue Tetrazolium Bromide (MTT) for tissue culture, 98%
CAS:Formula:C18H16N5SBrPurity:min. 98%Color and Shape:Yellow, Crystalline powder, Clear, YellowMolecular weight:414.32
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