CAS 2982502-32-7
:FXR agonist 9
Description:
FXR agonist 9, identified by its CAS number 2982502-32-7, is a synthetic compound that acts as a selective agonist for the farnesoid X receptor (FXR), a nuclear receptor involved in the regulation of bile acid, lipid, and glucose metabolism. This compound is characterized by its ability to modulate metabolic pathways, making it a subject of interest in the study of metabolic disorders, including non-alcoholic fatty liver disease and diabetes. FXR agonists typically exhibit properties such as enhancing bile acid synthesis and promoting glucose homeostasis. The chemical structure of FXR agonist 9 likely includes specific functional groups that confer its agonistic activity, although detailed structural information is not provided here. Its pharmacological profile may include effects on lipid profiles and anti-inflammatory properties, contributing to its potential therapeutic applications. As with many research compounds, the safety, efficacy, and mechanism of action of FXR agonist 9 would require further investigation through preclinical and clinical studies.
Formula:C28H30N2O5
InChI:InChI=1S/C28H30N2O5/c1-28(2,3)20-13-15-22(16-14-20)35-17-7-12-25(31)30-24-11-5-4-10-23(24)26(32)29-21-9-6-8-19(18-21)27(33)34/h4-6,8-11,13-16,18H,7,12,17H2,1-3H3,(H,29,32)(H,30,31)(H,33,34)
InChI key:PXVVIZGYRBAVHT-UHFFFAOYSA-N
SMILES:CC(C)(C)C1=CC=C(C=C1)OCCCC(=O)NC2=CC=CC=C2C(=O)NC3=CC=CC(=C3)C(=O)O
Synonyms:- FXR agonist 9
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FXR agonist 9
CAS:FXR agonist9 (compound 26) is a selective, orally active partial agonist of FXR with an EC50 of 0.09 µM (maximum efficacy of 75.13%). It ameliorates the pathological features of fatty liver disease in mice induced by HFD and CCl4-related metabolic dysfunction.Formula:C28H30N2O5Color and Shape:SolidMolecular weight:474.55
