CAS 29851-57-8
:8-oxoadenosine
Description:
8-Oxoadenosine, also known as 8-oxo-adenosine, is a modified nucleoside that plays a significant role in cellular metabolism and signaling. It is derived from adenosine, with an oxygen atom added to the 8th position of the purine ring, resulting in a keto group. This modification can influence its biological activity and stability. 8-Oxoadenosine is known to participate in various biochemical pathways, including those related to oxidative stress and DNA repair, as it can be formed as a result of oxidative damage to nucleotides. Its presence in cells can affect cellular signaling and may be involved in the regulation of gene expression. The compound is soluble in water and exhibits properties typical of nucleosides, such as the ability to form hydrogen bonds. Due to its role in cellular processes, 8-oxoadenosine is of interest in research related to cancer, aging, and neurodegenerative diseases, where oxidative stress plays a critical role.
Formula:C10H13N5O5
InChI:InChI=1/C10H13N5O5/c11-7-4-8(13-2-12-7)15(10(19)14-4)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H,14,19)(H2,11,12,13)/t3-,5-,6-,9-/m1/s1
SMILES:C([C@@H]1[C@H]([C@H]([C@H](n2c3c(c(N)ncn3)nc2O)O1)O)O)O
Synonyms:- Adenosine, 8-Oxo-
- 6-amino-9-pentofuranosyl-7,9-dihydro-8H-purin-8-one
- 8-Oxoadenosine
- 8-Hydroxyadenosine
- 8-Hydroxyadenosine, , 8-Oxo-A
- 8-Hydroxy adenosine, anticancer antibiotics,oxidized nucleic acid adduct,precursor of phosmidosine (P-prodrug)
- 8-Oxoadenosine>
- Adenosine, 7,8-dihydro-8-oxo-
- 6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7,9-dihydro-1H-purin-8(2H)-one
- 7,8-Dihydro-8-oxoadenosine
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Found 8 products.
8-Oxoadenosine
CAS:Formula:C10H13N5O5Purity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:283.247,8-Dihydro-8-oxoadenosine
CAS:Formula:C10H15N5O5Purity:98%Color and Shape:SolidMolecular weight:285.25668-Hydroxyadenosine
CAS:8-Hydroxyadenosine (8-Oxoadenosine) is a purine nucleoside found in Torula yeast RNA.Formula:C10H13N5O5Purity:99.71%Color and Shape:SolidMolecular weight:283.248-Oxoadenosine
CAS:Controlled ProductApplications 8-Oxoadenosine (cas# 29851-57-8) is a useful research chemical.
Formula:C10H13N5O5Color and Shape:NeatMolecular weight:283.248-Hydroxyadenosine
CAS:8-Hydroxyadenosine (8-OHdG) is a purine nucleoside that is formed as a result of oxidative DNA damage. It is not an essential metabolite because it can be synthesized de novo. 8-OHdG has been shown to have potent anti-tumor activity in vitro and in vivo, which may be due to its ability to inhibit DNA replication. The biological effects of 8-OHdG are attributed to its ability to form hydrogen bonds with guanine residues in the double helix, and electrochemical detectors have been developed for its detection.Formula:C10H13N5O5Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:283.25 g/mol
