CAS 29851-57-8

8-oxoadenosine

Description:

8-Oxoadenosine, also known as 8-oxo-adenosine, is a modified nucleoside that plays a significant role in cellular metabolism and signaling. It is derived from adenosine, with an oxygen atom added to the 8th position of the purine ring, resulting in a keto group. This modification can influence its biological activity and stability. 8-Oxoadenosine is known to participate in various biochemical pathways, including those related to oxidative stress and DNA repair, as it can be formed as a result of oxidative damage to nucleotides. Its presence in cells can affect cellular signaling and may be involved in the regulation of gene expression. The compound is soluble in water and exhibits properties typical of nucleosides, such as the ability to form hydrogen bonds. Due to its role in cellular processes, 8-oxoadenosine is of interest in research related to cancer, aging, and neurodegenerative diseases, where oxidative stress plays a critical role.

Formula: C₁₀H₁₃N₅O₅

InChI: InChI=1/C10H13N5O5/c11-7-4-8(13-2-12-7)15(10(19)14-4)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H,14,19)(H2,11,12,13)/t3-,5-,6-,9-/m1/s1

InChI key: UEHOMUNTZPIBIL-UUOKFMHZSA-N

SMILES: C([C@@H]1[C@H]([C@H]([C@H](n2c3c(c(N)ncn3)nc2O)O1)O)O)O

Synonyms:

• Adenosine, 8-Oxo-
• 6-amino-9-pentofuranosyl-7,9-dihydro-8H-purin-8-one
• 8-Oxoadenosine
• 8-Hydroxyadenosine
• 8-Hydroxyadenosine, , 8-Oxo-A
• 8-Hydroxy adenosine, anticancer antibiotics,oxidized nucleic acid adduct,precursor of phosmidosine (P-prodrug)
• 8-Oxoadenosine&gt
• Adenosine, 7,8-dihydro-8-oxo-
• 6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7,9-dihydro-1H-purin-8(2H)-one
• 7,8-Dihydro-8-oxoadenosine

8-Oxoadenosine

CAS: 29851-57-8

Formula: C₁₀H₁₃N₅O₅

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 283.24

Ref: 3B-O0401

8-Hydroxyadenosine

CAS: 29851-57-8

8-Hydroxyadenosine

Formula: C₁₀H₁₃N₅O₅

Purity: ≥98%

Molecular weight: 283.24

Ref: 54-BUP20023

8-Hydroxyadenosine

CAS: 29851-57-8

Ref: 7W-GN9495

6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7,9-dihydro-1H-purin-8(2H)-one

CAS: 29851-57-8

Formula: C₁₀H₁₅N₅O₅

Purity: 98.0%

Color and Shape: Solid

Molecular weight: 285.2566

Ref: IN-DA00BDZJ

8-Hydroxyadenosine

CAS: 29851-57-8

8-Hydroxyadenosine (8-Oxoadenosine) is a purine nucleoside found in Torula yeast RNA.

Formula: C₁₀H₁₃N₅O₅

Purity: 99.71%

Color and Shape: Yellow Solid

Molecular weight: 283.2407

Ref: TM-TNU0199

8-Oxoadenosine

Controlled Product

CAS: 29851-57-8

Applications 8-Oxoadenosine (cas# 29851-57-8) is a useful research chemical.

Formula: C₁₀H₁₃N₅O₅

Color and Shape: Neat

Molecular weight: 283.24

Ref: TR-O847263

8-Hydroxyadenosine

CAS: 29851-57-8

8-Hydroxyadenosine (8-OHdG) is a purine nucleoside that is formed as a result of oxidative DNA damage. It is not an essential metabolite because it can be synthesized de novo. 8-OHdG has been shown to have potent anti-tumor activity in vitro and in vivo, which may be due to its ability to inhibit DNA replication. The biological effects of 8-OHdG are attributed to its ability to form hydrogen bonds with guanine residues in the double helix, and electrochemical detectors have been developed for its detection.

Formula: C₁₀H₁₃N₅O₅

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 283.25 g/mol

Ref: 3D-NH08494

8-oxoadenosine

CAS: 29851-57-8

Purity: 98.0%

Molecular weight: 283.243988

Ref: 10-F866477