CAS 299-75-2

Treosulfan

Description:

Treosulfan is a synthetic compound classified as a bifunctional alkylating agent, primarily used in chemotherapy for the treatment of certain cancers, particularly in conditioning regimens prior to stem cell transplantation. Its chemical structure features a sulfonate group, which contributes to its reactivity and ability to form cross-links with DNA, ultimately leading to cell death. Treosulfan is known for its relatively favorable safety profile compared to other alkylating agents, as it exhibits less toxicity to normal tissues. It is typically administered intravenously and is characterized by its solubility in water, which facilitates its use in clinical settings. The compound undergoes metabolic conversion in the body, leading to the formation of active metabolites that exert its therapeutic effects. Treosulfan's mechanism of action involves the formation of DNA cross-links, which disrupts replication and transcription processes in rapidly dividing cancer cells. Overall, treosulfan represents an important therapeutic option in oncology, particularly for patients undergoing hematopoietic stem cell transplantation.

Formula: C₆H₁₄O₈S₂

InChI: InChI=1S/C6H14O8S2/c1-15(9,10)13-3-5(7)6(8)4-14-16(2,11)12/h5-8H,3-4H2,1-2H3/t5-,6-/m0/s1

InChI key: InChIKey=YCPOZVAOBBQLRI-WDSKDSINSA-N

SMILES: [C@@H]([C@H](COS(C)(=O)=O)O)(COS(C)(=O)=O)O

Synonyms:

• (2S,3S)-2,3-dihydroxybutane-1,4-diyl dimethanesulfonate
• (2S,3S)-Threitol 1,4-bismethanesulfonate
• (S-(R*,R*))-1,2,3,4-Butanetetrol, 1,4-dimethanesulfonate
• 1,2,3,4-Butanetetrol, 1,4-dimethanesulfonate, (2S,3S)-
• 1,2,3,4-Butanetetrol, 1,4-dimethanesulfonate, (S-(R*,R*))-
• 2,3-Dihydroxybutane-1,4-Diyl Dimethanesulfonate
• <span class="text-smallcaps">L</span>-Threitol 1,4-bis(methanesulfonate)
• Cb 2562
• Cb 40067
• Ccris 2781
• DHB
• Dihydroxybusulfan
• Dihydroxymyleran
• Hsdb 6963
• L-Threitol 1,4-dimethanesulfonate
• L-Threitol, 1,4-bis(methanesulfonate)
• L-Threitol, 1,4-bismethanesulfonate
• L-Threityl dimesylate
• Nsc 39069
• Ovastat
• Threitol, 1,4-dimethanesulfonate, (2S,3S)-
• Threitol, 1,4-dimethanesulfonate, L-(+)-
• Threosulphan
• Trecondi
• Treosulfano
• Treosulfano [INN-Spanish]
• Treosulfanum
• Treosulfanum [INN-Latin]
• Treosulphan
• Tresulfan

Treosulfan

CAS: 299-75-2

Formula: C₆H₁₄O₈S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 278.3006

Ref: IN-DA00BF51

Treosulfan

CAS: 299-75-2

Treosulfan

Purity: ≥98%

Molecular weight: 278.3g/mol

Ref: 54-BUP15412

Treosulfan

CAS: 299-75-2

Formula: C₆H₁₄O₈S₂

Molecular weight: 278.29

Ref: 4Z-E-513

Treosulfan

CAS: 299-75-2

Treosulfan (NSC 39069) is a bifunctional alkylating agent used in the treatment of advanced ovarian cancer.Cost-effective and quality-assured.

Formula: C₆H₁₄O₈S₂

Purity: 99.26% - 99.75%

Color and Shape: Solid

Molecular weight: 278.3

Ref: TM-T17159

Treosulfan

CAS: 299-75-2

Applications Treosulfan (CAS# 299-75-2) is a useful research chemical compound.

Formula: C₆H₁₄O₈S₂

Color and Shape: Neat

Molecular weight: 278.3

Ref: TR-T220905