CymitQuimica logo

CAS 299-75-2

:

Treosulfan

Description:
Treosulfan is a synthetic compound classified as a bifunctional alkylating agent, primarily used in chemotherapy for the treatment of certain cancers, particularly in conditioning regimens prior to stem cell transplantation. Its chemical structure features a sulfonate group, which contributes to its reactivity and ability to form cross-links with DNA, ultimately leading to cell death. Treosulfan is known for its relatively favorable safety profile compared to other alkylating agents, as it exhibits less toxicity to normal tissues. It is typically administered intravenously and is characterized by its solubility in water, which facilitates its use in clinical settings. The compound undergoes metabolic conversion in the body, leading to the formation of active metabolites that exert its therapeutic effects. Treosulfan's mechanism of action involves the formation of DNA cross-links, which disrupts replication and transcription processes in rapidly dividing cancer cells. Overall, treosulfan represents an important therapeutic option in oncology, particularly for patients undergoing hematopoietic stem cell transplantation.
Formula:C6H14O8S2
InChI:InChI=1S/C6H14O8S2/c1-15(9,10)13-3-5(7)6(8)4-14-16(2,11)12/h5-8H,3-4H2,1-2H3/t5-,6-/m0/s1
InChI key:InChIKey=YCPOZVAOBBQLRI-WDSKDSINSA-N
SMILES:[C@@H]([C@H](COS(C)(=O)=O)O)(COS(C)(=O)=O)O
Synonyms:
  • (2S,3S)-2,3-dihydroxybutane-1,4-diyl dimethanesulfonate
  • (2S,3S)-Threitol 1,4-bismethanesulfonate
  • (S-(R*,R*))-1,2,3,4-Butanetetrol, 1,4-dimethanesulfonate
  • 1,2,3,4-Butanetetrol, 1,4-dimethanesulfonate, (2S,3S)-
  • 1,2,3,4-Butanetetrol, 1,4-dimethanesulfonate, (S-(R*,R*))-
  • 2,3-Dihydroxybutane-1,4-Diyl Dimethanesulfonate
  • <span class="text-smallcaps">L</span>-Threitol 1,4-bis(methanesulfonate)
  • Cb 2562
  • Cb 40067
  • Ccris 2781
  • See more synonyms
Found 8 products.