CAS 300-39-0
:3′,5′-Diiodo-L-tyrosine
Description:
3′,5′-Diiodo-L-tyrosine is a halogenated derivative of the amino acid tyrosine, characterized by the presence of two iodine atoms at the 3' and 5' positions of the aromatic ring. This compound is notable for its role in the biosynthesis of thyroid hormones, particularly thyroxine (T4), where iodination of tyrosine residues is a critical step. The molecular structure includes a phenolic hydroxyl group, which contributes to its reactivity and potential biological activity. 3′,5′-Diiodo-L-tyrosine is typically a white to off-white solid and is soluble in polar solvents. Its iodine substitutions enhance its lipophilicity and influence its interactions with biological systems. The compound is of interest in biochemical research, particularly in studies related to thyroid function and disorders. Additionally, it may serve as a precursor in the synthesis of iodinated compounds used in pharmaceuticals and diagnostic imaging. Safety and handling precautions should be observed due to the potential biological effects of iodine-containing compounds.
Formula:C9H9I2NO3
InChI:InChI=1S/C9H9I2NO3/c10-5-1-4(2-6(11)8(5)13)3-7(12)9(14)15/h1-2,7,13H,3,12H2,(H,14,15)/t7-/m0/s1
InChI key:InChIKey=NYPYHUZRZVSYKL-ZETCQYMHSA-N
SMILES:C([C@@H](C(O)=O)N)C1=CC(I)=C(O)C(I)=C1
Synonyms:- (2S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid
- 3,5-Diiodo-4-hydroxy-β-phenylalanine
- 3,5-Diiodo-<span class="text-smallcaps">L</span>-tyrosine
- 3,5-Diiodo-L-tyrosine
- 3,5-Iodo-L-tyrosine
- 3,5-L-Diiodotyrosine
- 3,5-diiodo-L-tyrosin
- <span class="text-smallcaps">L</span>-3,5-Diiodotyrosine
- <span class="text-smallcaps">L</span>-Tyrosine, 3,5-diiodo-
- Bijodtyrosin
- DIT (amino acid)
- H-Tyr(3,5-DiI)-OH
- NSC 4143
- Tyrosine, 3,5-diiodo-, <span class="text-smallcaps">L</span>-
- L-3,5-Diiodotyrosine
- L-Tyrosine, 3,5-diiodo-
- Tyrosine, 3,5-diiodo-, L-
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 12 products.
3,5-Diiodo-L-tyrosine Dihydrate
CAS:Formula:C9H9I2NO3·2H2OPurity:>98.0%(T)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:469.01Diiodotyrosine (3,5-Diiodo-L-tyrosine)
CAS:Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen functionFormula:C9H9I2NO3Color and Shape:White Off-White PowderMolecular weight:432.867193,5-Diiodo-L-tyrosine dihydrate
CAS:3,5-Diiodo-L-tyrosine dihydratePurity:≥98%Molecular weight:432.98g/molLiothyronine EP Impurity B
CAS:Formula:C9H9I2NO3Color and Shape:Off-White SolidMolecular weight:432.983,5-Diiodo-L-tyrosine dihydrate
CAS:3,5-Diiodo-L-tyrosine dihydrate is a natural product.Formula:C9H9I2NO3Purity:99.32%Color and Shape:SolidMolecular weight:432.983,5-Diiodo-L-tyrosine dihydrate
CAS:Formula:C9H9I2NO3·2H2OPurity:≥ 98.0%Color and Shape:Off-white, faint yellow or pale beige powderMolecular weight:469.013,5-Diiodo-tyrosine
CAS:Formula:C9H9I2NO3Purity:97%Color and Shape:Solid, Light yellow crystalline powderMolecular weight:432.9843,5-Diiodo-L-tyrosine
CAS:<p>3,5-Diiodo-L-tyrosine (3DILT) is an iodinated amino acid that can be used as a marker for human immunodeficiency virus (HIV) infection. It is synthesized by the reaction of 3,5-diiodotyrosine with L-tyrosine in the presence of a metal chelate and dinucleotide phosphate. This reaction proceeds via nucleophilic substitution on the aromatic ring with an iodide ion. The product is then purified to remove unreacted 3,5-diiodotyrosine and the metal chelate. 3DILT reacts with antibodies in a luminescence immunoassay to produce light that can be detected. The detection limit of this assay is 10 pg/mL.</p>Formula:C9H9I2NO3Purity:Min. 95%Molecular weight:432.98 g/mol
