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CAS 300-39-0

:

3′,5′-Diiodo-L-tyrosine

Description:
3′,5′-Diiodo-L-tyrosine is a halogenated derivative of the amino acid tyrosine, characterized by the presence of two iodine atoms at the 3' and 5' positions of the aromatic ring. This compound is notable for its role in the biosynthesis of thyroid hormones, particularly thyroxine (T4), where iodination of tyrosine residues is a critical step. The molecular structure includes a phenolic hydroxyl group, which contributes to its reactivity and potential biological activity. 3′,5′-Diiodo-L-tyrosine is typically a white to off-white solid and is soluble in polar solvents. Its iodine substitutions enhance its lipophilicity and influence its interactions with biological systems. The compound is of interest in biochemical research, particularly in studies related to thyroid function and disorders. Additionally, it may serve as a precursor in the synthesis of iodinated compounds used in pharmaceuticals and diagnostic imaging. Safety and handling precautions should be observed due to the potential biological effects of iodine-containing compounds.
Formula:C9H9I2NO3
InChI:InChI=1S/C9H9I2NO3/c10-5-1-4(2-6(11)8(5)13)3-7(12)9(14)15/h1-2,7,13H,3,12H2,(H,14,15)/t7-/m0/s1
InChI key:InChIKey=NYPYHUZRZVSYKL-ZETCQYMHSA-N
SMILES:C([C@@H](C(O)=O)N)C1=CC(I)=C(O)C(I)=C1
Synonyms:
  • (2S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid
  • 3,5-Diiodo-4-hydroxy-β-phenylalanine
  • 3,5-Diiodo-<span class="text-smallcaps">L</span>-tyrosine
  • 3,5-Diiodo-L-tyrosine
  • 3,5-Iodo-L-tyrosine
  • 3,5-L-Diiodotyrosine
  • 3,5-diiodo-L-tyrosin
  • <span class="text-smallcaps">L</span>-3,5-Diiodotyrosine
  • <span class="text-smallcaps">L</span>-Tyrosine, 3,5-diiodo-
  • Bijodtyrosin
  • See more synonyms
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