CAS 3017958-71-0

CHK1-IN-11

Formula: C₂₀H₂₂N₈O₂

InChI: InChI=1S/C20H22N8O2/c1-11-5-16(30-14-4-3-12(22)6-14)19(20(25-11)29-2)15-7-17(28-27-15)26-18-10-23-13(8-21)9-24-18/h5,7,9-10,12,14H,3-4,6,22H2,1-2H3,(H2,24,26,27,28)/t12-,14+/m0/s1

InChI key: BJSAQDGIPJPJDG-GXTWGEPZSA-N

SMILES: CC1=CC(=C(C(=N1)OC)C2=CC(=NN2)NC3=NC=C(N=C3)C#N)O[C@@H]4CC[C@@H](C4)N

Synonyms:

• CHK1-IN-11

CHK1-IN-11

CAS: 3017958-71-0

CHK1-IN-11 (Compound 1) is an orally active inhibitor of checkpoint kinase 1 (CHK1). It is utilized in research focused on cancers with oncogene amplification.

Formula: C₂₀H₂₂N₈O₂

Color and Shape: Solid

Molecular weight: 406.44

Ref: TM-T207353