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CAS 301836-41-9
:4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Description:
4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide, with the CAS number 301836-41-9, is a synthetic organic compound characterized by its complex molecular structure, which includes a benzamide moiety and an imidazole ring substituted with a benzodioxole and a pyridine group. This compound typically exhibits properties such as moderate solubility in organic solvents and potential bioactivity, making it of interest in medicinal chemistry. The presence of the benzodioxole and pyridine groups may contribute to its pharmacological properties, possibly influencing its interactions with biological targets. Additionally, the imidazole ring is known for its role in various biological processes, including enzyme catalysis and receptor binding. The compound's specific characteristics, such as melting point, boiling point, and spectral data, would be determined through experimental methods and may vary based on purity and environmental conditions. Overall, this compound represents a class of heterocyclic compounds that are often explored for their therapeutic potential.
Formula:C22H16N4O3
InChI:InChI=1S/C22H16N4O3/c23-21(27)13-4-6-14(7-5-13)22-25-19(20(26-22)16-3-1-2-10-24-16)15-8-9-17-18(11-15)29-12-28-17/h1-11H,12H2,(H2,23,27)(H,25,26)
InChI key:InChIKey=FHYUGAJXYORMHI-UHFFFAOYSA-N
SMILES:C(N)(=O)C1=CC=C(C=2NC(=C(N2)C3=CC=CC=N3)C=4C=C5C(=CC4)OCO5)C=C1
Synonyms:- 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
- 4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide
- Benzamide, 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]-
- Sb 431412
- Sb-431542
- Sb431542
- SB 43154
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Found 9 products.
SB 431542
CAS:Formula:C22H16N4O3Purity:>97.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:384.404-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
CAS:Formula:C22H16N4O3Purity:97%Color and Shape:SolidMolecular weight:384.3874SB431542
CAS:<p>SB431542</p>Formula:C22H16N4O3Purity:99%Color and Shape: pale yellow solidMolecular weight:384.38743g/molSB-431542
CAS:<p>SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective.</p>Formula:C22H16N4O3Purity:99.035% - >99.99%Color and Shape:SolidMolecular weight:384.39SB 431542 hydrate
CAS:Formula:C22H16N4O3·xH2OPurity:≥ 98.0%Color and Shape:White to off-white powderMolecular weight:384.39 (anhydrous)SB 431542
CAS:Controlled Product<p>Applications SB 431542 is a known Src family kinase inhibitor that effectively blocks the transforming growth factor-β1-induced cell migration and invasion in both established and primary carcinoma cells. Potent TGF-beta inhibitor.<br>References Tobias, B., et al.: Cancer. Chemother. Pharmacol., 70, 221 (2012); James, J., et al.: Molec. Cancer. Therap., 11, 930 (2012);<br></p>Formula:C22H16N4O3Color and Shape:NeatMolecular weight:384.39SB 431542
CAS:<p>Inhibitor of activin receptor-like kinases (ALK4, ALK5 and ALK7), members of TGFβ type I receptor family. Blocks activin- and TGFβ-mediated signaling and phosphorylation of Smad2 downstream. Suppresses tumor-promoting and tumor-suppressing effects of TGFβ. Promotes differentiation of human embryonic stem cells (hESCs), whilst sustaining mouse ESCs in the undifferentiated state.</p>Formula:C22H16N4O3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:384.4 g/mol
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