CAS 30195-30-3

7-Chloro-1,3-dihydro-5-(1H-pyrrol-2-yl)-2H-1,4-benzodiazepin-2-one

Description:

7-Chloro-1,3-dihydro-5-(1H-pyrrol-2-yl)-2H-1,4-benzodiazepin-2-one, with CAS number 30195-30-3, is a chemical compound belonging to the benzodiazepine class, which is known for its psychoactive properties. This compound features a benzodiazepine core structure, characterized by a fused benzene and diazepine ring, with a chlorine substituent at the 7-position and a pyrrole moiety at the 5-position. The presence of the chlorine atom typically enhances the compound's biological activity and lipophilicity. The pyrrole group may contribute to its pharmacological profile, potentially influencing receptor interactions. This compound is of interest in medicinal chemistry for its potential therapeutic applications, particularly in the fields of psychiatry and neurology. Its properties, such as solubility, stability, and reactivity, can vary based on environmental conditions and the presence of other functional groups. As with many benzodiazepines, it may exhibit anxiolytic, sedative, or anticonvulsant effects, although specific biological activities would require empirical investigation.

Formula: C₁₃H₁₀ClN₃O

InChI: InChI=1S/C13H10ClN3O/c14-8-3-4-10-9(6-8)13(11-2-1-5-15-11)16-7-12(18)17-10/h1-6,15H,7H2,(H,17,18)

InChI key: InChIKey=XWNMORIHKRROGW-UHFFFAOYSA-N

SMILES: ClC=1C=C2C(=NCC(=O)NC2=CC1)C3=CC=CN3

Synonyms:

• 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-pyrrol-2-yl-
• 2H-1,4-benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-(1H-pyrrol-2-yl)-
• 7-Chloro-1,3-dihydro-5-(1H-pyrrol-2-yl)-2H-1,4-benzodiazepin-2-one
• NSC 66020
• Ro 5-3335

7-Chloro-1,3-dihydro-5-(1H-pyrrol-2-yl)-2H-1,4-benzodiazepin-2-one

CAS: 30195-30-3

Formula: C₁₃H₁₀ClN₃O

Purity: %

Color and Shape: Solid

Molecular weight: 259.6910

Ref: IN-DA01ENNW

Ro5-3335

CAS: 30195-30-3

Ro5-3335

Purity: ≥98%

Molecular weight: 259.69g/mol

Ref: 54-BUP04213

Ro 5-3335

CAS: 30195-30-3

Formula: C₁₃H₁₀ClN₃O

Purity: >98.0%(HPLC)

Color and Shape: White to Light red to Green powder to crystal

Molecular weight: 259.69

Ref: 3B-R0223

Ro5-3335

CAS: 30195-30-3

Ro5-3335 (CBFβ-Runx1 inhibitor II) is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins.

Formula: C₁₃H₁₀ClN₃O

Purity: 99.42% - 99.87%

Color and Shape: Solid

Molecular weight: 259.69

Ref: TM-T4687

Ro 5-3335

CAS: 30195-30-3

Ro 5-3335 is a synthetic substance that inhibits the production of tumor necrosis factor-α (TNF-α), which is a cytokine that has been shown to induce choroidal neovascularization. Ro 5-3335 has synergistic effects with other drugs such as fluorescein, which can be used to study the progression of choroidal neovascularization in vivo. The anti-inflammatory effect of Ro 5-3335 may be due to its ability to inhibit the synthesis of TNF-α by binding to TNF-α response elements on DNA. This drug also induces cell death by inhibiting growth factor or messenger RNA production or by acting on specific cells such as toll-like receptor 2 and 4.

Formula: C₁₃H₁₀ClN₃O

Purity: Min. 95%

Molecular weight: 259.69 g/mol

Ref: 3D-FBA19530