CAS 302-17-0

Chloral hydrate

Description:

Chloral hydrate, with the CAS number 302-17-0, is a chemical compound that appears as a white crystalline solid or a colorless, viscous liquid. It is the hydrate form of chloral, which is a trichloroacetaldehyde. Chloral hydrate is known for its sedative and hypnotic properties and has historically been used in medicine as a sleep aid and anesthetic. The compound is soluble in water and alcohol, which facilitates its use in various formulations. Its chemical structure features three chlorine atoms attached to a carbon atom, contributing to its reactivity and potential toxicity. Chloral hydrate can undergo hydrolysis to form hydrochloric acid and other byproducts, and it is important to handle it with care due to its potential to cause respiratory depression and other side effects. Additionally, chloral hydrate can be involved in the formation of chlorinated byproducts in aquatic environments, raising environmental concerns. Overall, while it has legitimate medical applications, its use is regulated due to safety considerations.

Formula: C₂H₃Cl₃O₂

InChI: InChI=1/C2HCl3O.H2O/c3-2(4,5)1-6;/h1H;1H2

InChI key: InChIKey=RNFNDJAIBTYOQL-UHFFFAOYSA-N

SMILES: C(C(O)O)(Cl)(Cl)Cl

Synonyms:

• 1,1,1-Trichloro-2,2-Ethanediol
• 1,1,1-Trichloro-2,2-dihydroxyethane
• 1,1-Ethanediol, 2,2,2-trichloro-
• 2,2,2-Trichlorethan-1,1-diol
• 2,2,2-Trichloro-1,1-ethanediol
• 2,2,2-Trichloroethane-1,1-Diol
• 2,2,2-Tricloroetano-1,1-Diol
• Aquachloral
• Bi 3411
• Chloral, monohydrate
• Chloraldurat
• Chloralhydrat
• Choral Hydrate
• Dormal
• Escre
• Ethane-1,1-Diol, 2,2,2-Trichloro-
• Fagron
• Felsules
• Hydral
• Kessodrate
• Lorinal
• Noctec
• Nortec
• Nsc 3210
• Nycoton
• Nycton
• Phaldrone
• Rectules
• Sk-Chloral Hydrate
• Somni Sed
• Somnos
• Sontec
• Tosyl
• Trawotox
• Trichloroacetaldehyde Hydrate
• Trichloroacetaldehyde Monohydrate
• Chloral hydrate
• 1-Ethanediol,2,2,2-trichloro-1
• bi3411
• Amylofene
• Chloradorm
• 'GROUND JOINT SEPARATION AID'
• 2,2,2-TRICHLOROETHANE-1,1-DIOL HYDRATE
• 'SCHLIFF-AUF'

Chloral Hydrate

CAS: 302-17-0

Formula: C₂H₃Cl₃O₂

Purity: >99.0%(T)

Color and Shape: White or Colorless powder to crystal

Molecular weight: 165.39

Ref: 3B-C0073

Chloral hydrate, 99%

CAS: 302-17-0

Formula: C₂H₃Cl₃O₂

Purity: (Titration) ≥ 99.0%

Color and Shape: White crystalline powder or colourless crystals

Molecular weight: 165.40

Ref: 7W-GE3211

Chloral hydrate, BP, EP grade

CAS: 302-17-0

Formula: C₂H₃Cl₃O₂

Purity: 98.5 - 101.0 % (as is basis)

Color and Shape: Colourless, transparent crystals or white crystalline powder

Molecular weight: 165.40

Ref: 7W-GK3933

Chloralhydrate 1000 µg/mL in Acetonitrile

Controlled Product

CAS: 302-17-0

Formula: C₂H₃Cl₃O₂

Color and Shape: Single Solution

Molecular weight: 165.40

Ref: 04-YA11098000AL

Chloral hydrate 1000 µg/mL in Methanol

Controlled Product

CAS: 302-17-0

Formula: C₂H₃Cl₃O₂

Color and Shape: Single Solution

Molecular weight: 165.40

Ref: 04-GA09011102ME

Chloral Hydrate

Controlled Product

CAS: 302-17-0

Formula: C₂H₃Cl₃O₂

Color and Shape: White To Off-White

Molecular weight: 165.40

Ref: 86-MM1650.00

Chloralhydrate

Controlled Product

CAS: 302-17-0

Formula: C₂H₃Cl₃O₂

Color and Shape: White To Off-White

Molecular weight: 165.40

Ref: 04-C11098000

Trichloroacetaldehyde Hydrate

Controlled Product

CAS: 302-17-0

Stability Light Sensitive
Applications Trichloroacetaldehyde Hydrate is a useful chemical reagent used as a sedative/hypnotic agent. Studies have shown that when used in pediatric sedation side effects such as hallucination, excessive sleep and seizures were observed. It is sometimes administered to patients being treated with cyclophosphamide and it is known to inhibit some aldehyde dehydrogenases.This compound is suitable for aldehyde dehydrogenase (ALDH).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Costa, L., et al.: J. Pediatr., 160, 807 (2012); Munoz, M., et al.: J. Pediatr., 131, 787 (1997); Maki, P., & Sladek, N.: Biochem. Pharmacol., 45, 231 (1993)

Formula: C₂H₃Cl₃O₂

Color and Shape: White To Off-White

Molecular weight: 165.40

Ref: TR-T774055

Trichloroacetaldehyde-13C2 Hydrate

Controlled Product

CAS: 302-17-0

Formula: C₂H₃Cl₃O₂

Color and Shape: Neat

Molecular weight: 167.39

Ref: TR-T774057

Chloral hydrate

Controlled Product

CAS: 302-17-0

Chloral hydrate is a sedative and hypnotic drug that is used in the treatment of insomnia, anxiety disorders, and seizure disorders. It has also been used as an anticonvulsant and muscle relaxant. Chloral hydrate binds to the 5-HT2 receptors on neurons to produce its sedative effects. The therapeutic dose of chloral hydrate ranges from 1 to 3 g per day in adults, with a maximum dose of 12 g per day. Clinical studies have shown that chloral hydrate can cause liver damage when combined with other drugs such as acetaminophen or alcohol.

Formula: C₂H₃Cl₃O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 165.4 g/mol

Ref: 3D-FC45435