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CAS 3024545-79-4

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CDK7-IN-26

Formula:C22H22FN6OPS
Synonyms:
  • CDK7-IN-26
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  • CDK7-IN-26
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    CDK7-IN-26

    CAS:
    CDK7-IN-26 (compound 36) is an orally active CDK7 inhibitor with an IC50 of 7.4 nM. The compound effectively suppresses the growth of xenograft tumors derived from triple-negative breast cancer (TNBC) cell lines in vivo and has an IC50 of 0.15 μM for inhibiting MDA-MB-453 cells in vitro.
    Formula:C22H22FN6OPS
    Molecular weight:468.49

    Ref: TM-T208352