CAS 3029898-85-6

Formula: C36H31FN8O4

InChI: InChI=1S/C36H31FN8O4/c1-42(2)18-22-6-5-7-23(16-22)30-31-34(38-21-39-35(31)49-32(30)24-17-40-43(3)19-24)48-28-14-10-26(11-15-28)41-33(46)29-20-44(4)45(36(29)47)27-12-8-25(37)9-13-27/h5-17,19-21H,18H2,1-4H3,(H,41,46)

InChI key: WOAZQVRBSBTOAN-UHFFFAOYSA-N

SMILES: CN1C=C(C=N1)C2=C(C3=C(O2)N=CN=C3OC4=CC=C(C=C4)NC(=O)C5=CN(N(C5=O)C6=CC=C(C=C6)F)C)C7=CC=CC(=C7)CN(C)C

MerTK-IN-3

CAS: 3029898-85-6

MerTK-IN-3 (compound 11) is an orally active, selective inhibitor of MerTK, exhibiting IC50 values of 21.5 nM for MerTK and 991.3 nM for Tyro3. It is applicable in colon cancer research.

Formula: C₃₆H₃₁FN₈O₄

Color and Shape: Solid

Molecular weight: 658.68

Ref: TM-T211138