CAS 3033480-42-8

USP1-IN-7

Formula: C₂₇H₂₃F₄N₇O₂

InChI: InChI=1S/C27H23F4N7O2/c1-36-12-18(27(29,30)31)35-24(36)16-6-4-14(5-7-16)11-38-23-17(37(2)26(38)39)10-32-22(20(23)28)19-21(15-8-9-15)33-13-34-25(19)40-3/h4-7,10,12-13,15H,8-9,11H2,1-3H3

InChI key: JDTDBFVYUWMKSG-UHFFFAOYSA-N

SMILES: CN1C=C(N=C1C2=CC=C(C=C2)CN3C4=C(C(=NC=C4N(C3=O)C)C5=C(N=CN=C5OC)C6CC6)F)C(F)(F)F

Synonyms:

• USP1-IN-7

USP1-IN-7

CAS: 3033480-42-8

USP1-IN-7 (Compound 3), a potent inhibitor of ubiquitin specific peptidase 1 (USP1) and its cofactor UAF1, exhibits an inhibition concentration (IC 50) of ≤50 nM. It also effectively inhibits the proliferation of MDA-MB-436 cells at similar concentrations [1].

Formula: C₂₇H₂₃F₄N₇O₂

Color and Shape: Solid

Molecular weight: 553.51

Ref: TM-T87601