CAS 3034-38-6
:5-Nitroimidazole
Description:
5-Nitroimidazole is a chemical compound characterized by its imidazole ring structure, which is a five-membered heterocyclic compound containing two nitrogen atoms. This compound features a nitro group (-NO2) attached to the carbon atom adjacent to one of the nitrogen atoms in the imidazole ring, which contributes to its reactivity and biological activity. It is typically a yellow to orange crystalline solid that is soluble in organic solvents but has limited solubility in water. 5-Nitroimidazole is known for its antimicrobial properties and is often used in pharmaceuticals, particularly as an antiprotozoal and antibacterial agent. Its mechanism of action involves the reduction of the nitro group, leading to the formation of reactive intermediates that can damage DNA and inhibit nucleic acid synthesis in target organisms. Additionally, it is important to handle this compound with care due to its potential toxicity and environmental impact. Overall, 5-Nitroimidazole serves as a significant compound in medicinal chemistry and microbiology.
Formula:C3H3N3O2
InChI:InChI=1S/C3H3N3O2/c7-6(8)3-1-4-2-5-3/h1-2H,(H,4,5)
InChI key:InChIKey=VYDWQPKRHOGLPA-UHFFFAOYSA-N
SMILES:N(=O)(=O)C1=CN=CN1
Synonyms:- 1H-4-Nitroimidazole
- 1H-5-Nitroimidazole
- 1H-Imidazole, 4-nitro-
- 1H-Imidazole, 5-nitro-
- 4(5)-Nitroimidazole
- 4-Nitro-1H-imidazole
- 5-Nitro-1H-imidazole
- 5-Nitroimidazole
- Imidazole, 4(or 5)-nitro-
- Imidazole, 4-nitro-
- NSC 50359
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 14 products.
4-Nitroimidazole
CAS:Formula:C3H3N3O2Purity:>98.0%(GC)Color and Shape:White to Light yellow powder to crystalMolecular weight:113.084-Nitroimidazole, 97%
CAS:<p>This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci</p>Formula:C3H3N3O2Purity:97%Color and Shape:Powder, White to pale cream to pale yellowMolecular weight:113.084-Nitro-1H-imidazole
CAS:<p>4-Nitro-1H-imidazole</p>Formula:C3H3N3O2Purity:98%Color and Shape: off-white powderMolecular weight:113.07481g/molMetronidazole EP Impurity B (4-Nitroimidazole)
CAS:Formula:C3H3N3O2Color and Shape:White To Off-White SolidMolecular weight:113.084-Nitroimidazole
CAS:Formula:C3H3N3O2Purity:≥ 97%Color and Shape:White to off-white or yellow powderMolecular weight:113.08GB/T 21318-2007, SN/T 1928-2007 10 Nitroimidazoles 100 µg/mL in Methanol
CAS:Controlled ProductColor and Shape:Mixture4-Nitro-1H-imidazole
CAS:Controlled Product<p>Applications Metronidazole (M338880) derivative, an antibacterial in the treatment of rosacea and inflammatory bowel disease.<br>References Khan, K. et al.; Am. J. Gastroenterol. 106, 661 (2011)<br></p>Formula:C3H3N3O2Color and Shape:NeatMolecular weight:113.074-Nitroimidazole
CAS:<p>4-Nitroimidazole has a redox potential that is well suited to the reduction of nitro groups. It is an antimicrobial agent that inhibits the growth of microorganisms by inhibiting DNA synthesis. 4-Nitroimidazole can be used for the treatment of infectious diseases such as tuberculosis, leprosy, and brucellosis. In rat liver microsomes, 4-nitroimidazole reacts with NADPH to produce a nitro group and an imidazole ring with a new configuration. The reaction mechanism is based on electron transfer from NADPH to the nitro group in 4-nitroimidazole via a series of reactions that involve cytochrome P450 enzymes. This reaction has kinetic energy and matrix effects that affect its pharmacokinetics and pharmacodynamics.</p>Formula:C3H3N3O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:113.07 g/mol
