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CAS 304-20-1

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Hydralazine hydrochloride

Description:
Hydralazine hydrochloride is a pharmaceutical compound primarily used as an antihypertensive agent to manage high blood pressure. It is classified as a vasodilator, which means it works by relaxing the blood vessels, thereby reducing the workload on the heart. The chemical formula for hydralazine hydrochloride is C8H8N4·HCl, indicating it contains a hydrazine moiety, which is essential for its biological activity. This compound is typically administered orally or intravenously and is known for its rapid onset of action. Hydralazine hydrochloride is characterized by its white to off-white crystalline appearance and is soluble in water, making it suitable for various formulations. Common side effects may include headache, palpitations, and gastrointestinal disturbances. It is important to monitor patients for potential adverse reactions, such as lupus-like syndrome, especially with long-term use. Overall, hydralazine hydrochloride plays a significant role in the management of hypertension, particularly in cases where other treatments may not be effective.
Formula:C8H8N4·ClH
InChI:InChI=1S/C8H8N4.ClH/c9-11-8-7-4-2-1-3-6(7)5-10-12-8;/h1-5H,9H2,(H,11,12);1H
InChI key:InChIKey=ZUXNZUWOTSUBMN-UHFFFAOYSA-N
SMILES:N(N)=C1C=2C(C=NN1)=CC=CC2.Cl
Synonyms:
  • (Phthalazin-1-yl)hydrazine hydrochloride
  • 1(2H)-Phthalazinone hydrazone
  • 1(2H)-Phthalazinone, hydrazone, monohydrochloride
  • 1-Hydrazinophthalazine hydrochloride
  • 1-Hydrazinophthalazine monohydrochloride
  • 1-Hydrazinylphthalazine
  • 1-Hydrazinylphthalazine Hydrochloride (1:1)
  • 1-Hydrazinylphthalazine hydrochloride
  • Apresoline hydrochloride
  • Apulon
  • See more synonyms
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