CAS 30516-87-1
:Azidothymidine
Description:
Azidothymidine, commonly known as AZT or zidovudine, is an antiretroviral medication primarily used in the treatment of HIV/AIDS. It is a nucleoside reverse transcriptase inhibitor (NRTI) that works by inhibiting the reverse transcriptase enzyme, thereby preventing the replication of the virus. AZT is characterized by its azido group, which distinguishes it from thymidine, a naturally occurring nucleoside. The compound is typically administered in its phosphate form, which is activated within the body to exert its antiviral effects. AZT is known for its ability to reduce the viral load in patients and improve immune function, although it may also cause side effects such as bone marrow suppression and gastrointestinal issues. Its chemical structure includes a pyrimidine base, and it is soluble in water, making it suitable for various formulations. AZT has played a significant role in HIV treatment regimens and remains a critical component in the management of the disease, particularly in combination therapies.
Formula:C10H13N5O4
InChI:InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
InChI key:InChIKey=HBOMLICNUCNMMY-XLPZGREQSA-N
SMILES:O=C1N([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C=C(C)C(=O)N1
Synonyms:- 1-(3-Azido-2,3-Dideoxy-Beta-D-Ribofuranosyl)Thymine
- 1-(3-azido-2,3-dideoxy-beta-D-threo-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
- 1-(3-azido-2,3-dideoxypentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
- 1-(4-Azido-5-Hydroxymethyl-Tetrahydro-Furan-2-Yl)-5-Methyl-1H-Pyrimidine-2,4-Dione
- 1-[(3xi)-3-azido-2,3-dideoxy-beta-D-glycero-pentofuranosyl]-5-methylpyrimidine-2,4(1H,3H)-dione
- 3'-Azido-3'-Deoxythymidine
- 3'-Azido-3'-desoxythymidine
- 3'-Azido-3'-thymidine
- 3'-Azidothymidine
- 3'-Deoxy-3'-azidothymidine
- 3-Azido-3-deoxy-thymidine
- 3′-Azt
- AZT
- AZT (pharmaceutical)
- Azidothymidine
- Azitidin
- Bw-A 509U
- Compound S
- Nsc 602670
- Retrovir
- Retrovir IV
- Retrovis
- Thymidine, 3'-azido-3'-deoxy-
- Timazid
- Viro-Z
- ZDV
- ZVD
- Zido-H
- See more synonyms
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Found 24 products.
3'-Azido-3'-deoxythymidine, 98%
CAS:Anti-viral agentFormula:C10H13N5O4Purity:98%Color and Shape:White to yellow, PowderMolecular weight:267.25ZIDOVUDINE CRS
CAS:ZIDOVUDINE CRSFormula:C10H13N5O4Color and Shape:White. Light Brown. Powder.Molecular weight:267.2413Zidovudine
CAS:ZidovudineFormula:C10H13N5O4Purity:99.3%Color and Shape:Off-WhiteMolecular weight:267.09675Zidovudine
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C10H13N5O4Color and Shape:White Light Yellow Crystalline SolidMolecular weight:267.24 g/molThymidine, 3'-azido-3'-deoxy-
CAS:Formula:C10H13N5O4Purity:98%Color and Shape:SolidMolecular weight:267.2413Zidovudine
CAS:Zidovudine, a synthetic dideoxynucleoside, blocks DNA replication by inhibiting DNA polymerase after activation.Formula:C10H13N5O4Purity:99.84% - 99.91%Color and Shape:White To Off-White CrystalsMolecular weight:267.243'-Azido-3'-deoxythymidine
CAS:Formula:C10H13N5O4Purity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:267.253'-Azido-3'-deoxythymidine
CAS:3'-Azido-3'-deoxythymidineFormula:C10H13N5O4Purity:98%Color and Shape: off-white solidMolecular weight:267.24g/mol3''-Azido-3''-deoxythymidine
CAS:Formula:C10H13N5O4Purity:≥ 98.0%Color and Shape:White to off-white crystalline powderMolecular weight:267.243'-Azido-3'-deoxythymidine, Methyl-d3
CAS:Controlled ProductApplications A deuterated, potent and selective inhibitor of HIV-1 replication.
References Mitsuya, H., et al.: Nature, 325, 773 (1987), Brehm, J., et al.: Biochem., 47, 14020 (2008), Paredes, R., et al.: J. Virol., 83, 2038 (2009), Wan, J., et al.: J. Med. Chem., 52, 1144 (2009), Mainardes, R., et al.: J. Pharm. Sci., 98, 257 (2009),Formula:C10H10D3N5O4Color and Shape:Off White SolidMolecular weight:270.263'-Azido-3'-deoxythymidine
CAS:Controlled ProductApplications A potent and selective inhibitor of HIV-1 replication.
References Mitsuya, H., et al.: Nature, 325, 773 (1987), Brehm, J., et al.: Biochem., 47, 14020 (2008), Paredes, R., et al.: J. Virol., 83, 2038 (2009), Wan, J., et al.: J. Med. Chem., 52, 1144 (2009), Mainardes, R., et al.: J. Pharm. Sci., 98, 257 (2009),Formula:C10H13N5O4Color and Shape:White To YellowMolecular weight:267.24Zidovudine
CAS:Inhibitor of reverse transcriptaseFormula:C10H13N5O4Purity:Min. 95%Color and Shape:Off-White PowderMolecular weight:267.24 g/mol1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS:Formula:C10H13N5O4Purity:98%Color and Shape:SolidMolecular weight:267.2453-Azido-3-Deoxythymidine extrapure, 99%
CAS:Formula:C10H13N5O4Purity:min. 99.0%Color and Shape:White, Crystalline powderMolecular weight:267.3
![1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF358376.jpg&w=3840&q=75)
