CAS 3055031-36-9

1,5-Naphthyridin-2(1H)-one, 3-amino-4-(7-fluoro-1H-indazol-4-yl)-7,8-dimethyl-

Formula: C₁₇H₁₄FN₅O

InChI: InChI=1S/C17H14FN5O/c1-7-5-20-16-12(13(19)17(24)22-14(16)8(7)2)9-3-4-11(18)15-10(9)6-21-23-15/h3-6H,19H2,1-2H3,(H,21,23)(H,22,24)

InChI key: CFWJQQWLNIWVCH-UHFFFAOYSA-N

SMILES: CC1=CN=C2C(=C(C(=O)NC2=C1C)N)C3=C4C=NNC4=C(C=C3)F

Synonyms:

• 1,5-Naphthyridin-2(1H)-one, 3-amino-4-(7-fluoro-1H-indazol-4-yl)-7,8-dimethyl-

PKMYT1-IN-9

CAS: 3055031-36-9

PKMYT1-IN-9 is a highly selective, orally active inhibitor of PKMYT1 with an IC₅₀ of 4.4 nM. It exhibits greater selectivity for PKMYT1 compared to WEE1, for which the IC₅₀ is 32.4 μM. Additionally, PKMYT1-IN-9 demonstrates antitumor activity.

Formula: C₁₇H₁₄FN₅O

Color and Shape: Solid

Molecular weight: 323.324

Ref: TM-T206301