CAS 3056-17-5

Stavudine

Description:

Stavudine, also known as d4T, is an antiretroviral medication primarily used in the treatment of HIV/AIDS. It belongs to the class of nucleoside reverse transcriptase inhibitors (NRTIs) and works by inhibiting the reverse transcriptase enzyme, which is crucial for viral replication. Stavudine is a synthetic analog of thymidine and is characterized by its ability to interfere with the viral life cycle, thereby reducing the viral load in infected individuals. The chemical formula of stavudine is C10H12N2O4, and it has a molecular weight of approximately 224.23 g/mol. It is typically administered orally and is known for its relatively low cost compared to other antiretroviral drugs. However, stavudine is associated with several side effects, including peripheral neuropathy and lactic acidosis, which necessitate careful monitoring during treatment. Due to its toxicity profile, it is often used in combination with other antiretroviral agents to enhance efficacy and minimize adverse effects.

Formula: C₁₀H₁₂N₂O₄

InChI: InChI=1/C10H14N2O4/c1-6-4-12(10(15)11-9(6)14)8-3-2-7(5-13)16-8/h2-3,6-8,13H,4-5H2,1H3,(H,11,14,15)

InChI key: InChIKey=XNKLLVCARDGLGL-JGVFFNPUSA-N

SMILES: O=C1N([C@@H]2O[C@H](CO)C=C2)C=C(C)C(=O)N1

Synonyms:

• 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione
• 1-[5-(Hydroxymethyl)-2,5-Dihydrofuran-2-Yl]-5-Methyl-Hexahydropyrimidine-2,4-Dione
• 2',3'-Didehydro-3'-Deoxythymidine
• 2,4(1H,3H)-Pyrimidinedione, 1-[(2R,5S)-2,5-dihydro-5-(hydroxymethyl)-2-furanyl]-5-methyl-
• 2′,3′-Didehydro-2′,3′-dideoxythymidine
• 2′,3′-Didehydro-3′-deoxythymidine
• 2′-Thymidinene, 3′-deoxy-
• 3'-Deoxy-2',3'-Didehydrothymidine
• 3'-Deoxythymidin-2'-Ene
• 3′-Deoxy-2′,3′-didehydrothymidine
• Avostav
• Bmy 27857
• D 4T (nucleoside)
• Melxicap
• NSC 163661
• Sanilvudine
• Staduvine
• Stavir
• Thymidine, 2′,3′-didehydro-3′-deoxy-
• Thymine, 1-(2,3-dideoxy-β-<span class="text-smallcaps">D</span>-glycero-pent-2-enofuranosyl)-
• Virostav
• Zerit
• Thymine, 1-(2,3-dideoxy-β-D-glycero-pent-2-enofuranosyl)-
• 2’,3’-didehydro-3’-deoxy-thymidin
• 2',3'-ANHYDROTHYMIDINE
• 1-(5-(HYDROXYMETHYL)-2,5-DIHYDROFURAN-2-YL)-5-METHYLDIHYDROPYRIMIDINE-2,4(1H,3H)-DIONE
• Stavudine(DT4)
• Stavudine(D4T)
• 1-(2,3-dideoxy-beta-d-glycero-pent-2-enofuranosyl)-thymin
• 2’,3’-dideoxy-2’,3’-didehydrothymidine
• D4T
• 1-(2,3-dideoxy-β-d-glycero-pent-2-enofuranosyl)thymine
• 2',3'-Didehydro-3'-deoxythymidine, D4t, BMY-27857, Zerit
• 1-((2R,5S)-5-HYDROXYMETHYL-2,5-DIHYDRO-FURAN-2-YL)-5-METHYL-1H-PYRIMIDINE-2,4-DIONE
• 2',3'-DIHYDRO-2',3'-DEOXYTHYMIDINE
• 2',3'-Didehydro-2',3'-dideoxythymidine
• 1-[2,3-DIDEOXY-BETA-D-GLYCERO-PENT-2-ENOFURANOSYL]THYMINE

STAVUDINE CRS

CAS: 3056-17-5

STAVUDINE CRS

Formula: C₁₀H₁₂N₂O₄

Color and Shape: Powder

Molecular weight: 224.2133

Ref: 41-Y0000408

STAVUDINE FOR SYSTEM SUITABILITY CRS

CAS: 3056-17-5

STAVUDINE FOR SYSTEM SUITABILITY CRS

Formula: C₁₀H₁₂N₂O₄

Color and Shape: Powder

Molecular weight: 224.2133

Ref: 41-Y0000421

STAVUDINE RS

CAS: 3056-17-5

STAVUDINE RS

Formula: C₁₀H₁₂N₂O₄

Color and Shape: Powder

Molecular weight: 224.2133

Ref: 41-ICRS1419

Stavudine

CAS: 3056-17-5

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₁₀H₁₂N₂O₄

Color and Shape: Powder

Molecular weight: 224.21

Ref: 45-1620209

Thymidine, 2',3'-didehydro-3'-deoxy-

CAS: 3056-17-5

Formula: C₁₀H₁₂N₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 224.2133

Ref: IN-DA0030JY

Stavudine

CAS: 3056-17-5

Stavudine (BMY-27857), a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.

Formula: C₁₀H₁₂N₂O₄

Purity: 99.01% - 99.88%

Color and Shape: White Powder

Molecular weight: 224.21

Ref: TM-T1404

Stavudine-13C-d3

CAS: 3056-17-5

Formula: C₉₁₃CH₉D₃N₂O₄

Color and Shape: White To Off-White Solid

Molecular weight: 228.23

Ref: 4Z-S-191

Stavudine

CAS: 3056-17-5

Formula: C₁₀H₁₂N₂O₄

Color and Shape: White To Off-White Solid

Molecular weight: 224.22

Ref: 4Z-S-192

Zidovudine EP Impurity A

CAS: 3056-17-5

Formula: C₁₀H₁₂N₂O₄

Color and Shape: White To Off-White Solid

Molecular weight: 224.22

Ref: 4Z-Z-084

1-((2R,5S)-5-(Hydroxymethyl)-2,5-Dihydrofuran-2-Yl)-5-Methylpyrimidine-2,4(1H,3H)-Dione

CAS: 3056-17-5

1-((2R,5S)-5-(Hydroxymethyl)-2,5-Dihydrofuran-2-Yl)-5-Methylpyrimidine-2,4(1H,3H)-Dione

Purity: 97%

Molecular weight: 224.21g/mol

Ref: 54-OR1008882

Stavudine

CAS: 3056-17-5

Stavudine

Purity: ≥98%

Molecular weight: 224.21g/mol

Ref: 54-BUP17036

Stavudine

CAS: 3056-17-5

Formula: C₁₀H₁₂N₂O₄

Purity: ≥ 98.0%

Color and Shape: White powder

Molecular weight: 224.21

Ref: 7W-GP1591

2',3'-Didehydro-3'-deoxythymidine

CAS: 3056-17-5

Formula: C₁₀H₁₂N₂O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 224.22

Ref: 3B-D3580

Stavudine

Controlled Product

CAS: 3056-17-5

Formula: C₁₀H₁₂N₂O₄

Color and Shape: Neat

Molecular weight: 224.21

Ref: 86-MM0534.00

Stavudine 100 µg/mL in Acetonitrile

CAS: 3056-17-5

Formula: C₁₀H₁₂N₂O₄

Color and Shape: Single Solution

Molecular weight: 224.21

Ref: 04-A16974260AL-100

Stavudine

Controlled Product

CAS: 3056-17-5

Impurity Zidovudine EP Impurity A
Applications Stavudine (Zidovudine EP Impurity A) is used as an antiviral. A reverse transcriptase inhibitor.
References Mansuri, M.M., et al.: Antimicrob. Ag. Chemother., 34, 637 (1990), Cretton, E.M., et al.: Antimicrob. Ag. Chemother., 37, 1816 (1993), Browne, M.J., et al.: J. Infec. Dis., 167, 21 (1993)

Formula: C₁₀H₁₂N₂O₄

Color and Shape: White

Molecular weight: 224.21

Ref: TR-S685250

Stavudine

CAS: 3056-17-5

Anti-viral; reverse transcriptase inhibitor

Formula: C₁₀H₁₂N₂O₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 224.22 g/mol

Ref: 3D-ND07118

Stavudine - Bio-X ™

CAS: 3056-17-5

Stavudine is an antiviral, reverse transcriptase inhibitor that is used to treat HIV/AIDS. It belongs to the group of nucleoside analogues of thymidine that is converted into stavudine monophosphate. Stavudine works by inhibiting viral replication by preventing the incorporation of viral dNTPs into the growing DNA chain, thus blocking DNA synthesis.

Formula: C₁₀H₁₂N₂O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 224.21 g/mol

Ref: 3D-BD164571

Sanilvudine

CAS: 3056-17-5

Formula: C₁₀H₁₂N₂O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 224.216

Ref: 10-F404709

Zidovudine EP Impurity A

CAS: 3056-17-5

Formula: C₁₀H₁₂N₂O₄

Molecular weight: 224.22

Ref: ST-EA-CP-Z6001