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CAS 3058199-58-6

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    MCB-22-174

    CAS:
    MCB-22-174 is a potent agonist of Piezo1 with an EC50 value of 6.28 µM. It activates Ca2+-related extracellular signal-regulated kinase and calcium-calmodulin (CaM)-dependent protein kinase II (CaMKII) pathways, and it promotes mesenchymal stem cell osteogenic differentiation, indicating its potential application in the study of disuse osteoporosis (OP).
    Formula:C16H14DCl2N5OS2
    Molecular weight:429.37

    Ref: TM-T207793