CAS 3059496-10-2

Formula: C53H68ClF2N9O8S

InChI: InChI=1S/C53H68ClF2N9O8S/c1-30(2)43(61(6)51(70)53(56)12-16-63(17-13-53)49(68)46(54)55)47(66)59-39-25-41-58-40(28-74-41)33-22-32-10-8-14-64-44(32)35(23-33)37(26-52(4,5)29-73-50(69)38-11-9-15-65(60-38)48(39)67)45(64)36-24-34(62-18-20-72-21-19-62)27-57-42(36)31(3)71-7/h22-24,27-28,30-31,38-39,43,46,60H,8-21,25-26,29H2,1-7H3,(H,59,66)/t31-,38-,39-,43-,46-/m0/s1

InChI key: JAPAXSDAYQBFIJ-YUBGLVCHSA-N

SMILES: C[C@@H](C1=C(C=C(C=N1)N2CCOCC2)C3=C4CC(COC(=O)[C@@H]5CCCN(N5)C(=O)[C@H](CC6=NC(=CS6)C7=CC8=C(C4=C7)N3CCC8)NC(=O)[C@H](C(C)C)N(C)C(=O)C9(CCN(CC9)C(=O)[C@H](F)Cl)F)(C)C)OC

KRAS inhibitor-38

CAS: 3059496-10-2

KRAS Inhibitor-38 (Example 18) is a potent inhibitor capable of effectively suppressing the activity of KRAS G12C, KRAS G12D, and KRAS G12V in vivo.

Formula: C₅₃H₆₈ClF₂N₉O₈S

Color and Shape: Solid

Molecular weight: 1064.68

Ref: TM-T201113