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CAS 306296-47-9

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Vicriviroc

Description:
Vicriviroc is a small molecule that functions as a CCR5 antagonist, primarily developed for the treatment of HIV infection. It selectively binds to the CCR5 co-receptor on the surface of immune cells, inhibiting the entry of HIV into these cells and thereby preventing viral replication. The compound is characterized by its ability to block the interaction between HIV and the CCR5 receptor, which is crucial for the virus's ability to infect host cells. Vicriviroc has been studied in clinical trials for its efficacy and safety profile, demonstrating potential benefits in patients with CCR5-tropic HIV strains. Its chemical structure includes a complex arrangement of carbon, hydrogen, nitrogen, and oxygen atoms, contributing to its pharmacological properties. As with many antiretroviral agents, monitoring for potential side effects and resistance development is essential during treatment. Overall, Vicriviroc represents a significant advancement in the therapeutic options available for managing HIV infection, particularly in cases where traditional therapies may not be effective.
Formula:C28H38F3N5O2
InChI:InChI=1S/C28H38F3N5O2/c1-19-16-35(14-15-36(19)24(17-38-5)22-6-8-23(9-7-22)28(29,30)31)27(4)10-12-34(13-11-27)26(37)25-20(2)32-18-33-21(25)3/h6-9,18-19,24H,10-17H2,1-5H3/t19-,24-/m0/s1
InChI key:InChIKey=CNPVJJQCETWNEU-CYFREDJKSA-N
SMILES:[C@@H](COC)(N1[C@@H](C)CN(CC1)C2(C)CCN(C(=O)C=3C(C)=NC=NC3C)CC2)C4=CC=C(C(F)(F)F)C=C4
Synonyms:
  • (4,6-Dimethyl-5-pyrimidinyl)[4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methyl-1-piperidinyl]methanone
  • 5-({4-[(3S)-4-{(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl}-3-methylpiperazin-1-yl]-4-methylpiperidin-1-yl}carbonyl)-4,6-dimethylpyrimidine
  • 5-[4-[4-[2-methoxy-1(R)-[4-(trifluoromethyl)phenyl]ethyl]-3(S)-methylpiperazin-1-yl]-4-methylpiperidin-1-ylcarbonyl]-4,6-dimethylpyrimidine
  • Methanone, (4,6-dimethyl-5-pyrimidinyl)[4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methyl-1-piperidinyl]-
  • Mk 7690
  • Piperidine, 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methyl-
  • Sch-417690
  • Sch-D
  • Vicriviroc
  • Vicroviroc
Found 4 products.