
CAS 3069891-91-1
:Formula:C21H22Cl2N4O3
InChI:InChI=1S/C21H22Cl2N4O3/c1-11-8-24-19(25-9-11)21(2,3)20(30)26-10-12-6-14(22)17(15(23)7-12)13-4-5-16(28)27-18(13)29/h6-9,13H,4-5,10H2,1-3H3,(H,26,30)(H,27,28,29)
InChI key:VKROEWYACWPSOG-UHFFFAOYSA-N
SMILES:CC1=CN=C(N=C1)C(C)(C)C(=O)NCC2=CC(=C(C(=C2)Cl)C3CCC(=O)NC3=O)Cl
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NEK7 degrader-1
CAS:NEK7 degrader-1 is a molecular glue degrader (DC₅₀ = 0.1 nM) that inhibits caspase-1 and IL-1β release.Formula:C21H22Cl2N4O3Purity:97.02%Molecular weight:449.33N-(3,5-Dichloro-4-(2,6-dioxopiperidin-3-yl)benzyl)-2-methyl-2-(5-methylpyrimidin-2-yl)propanamide
CAS:Purity:95%Molecular weight:G/Mol



