CAS 3080678-93-6
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PROTAC LRRK2 Degrader-2
CAS:PROTAC LRRK2 Degrader-2 is a PROTAC-based degrader targeting LRRK2 with a DC50 of 0.14 nM. It recruits LRRK2 or its mutants to cereblon E3 ubiquitin ligase, facilitating the targeted ubiquitination and subsequent proteasomal degradation of LRRK2. PROTAC LRRK2 Degrader-2 is applicable in Parkinson's disease research.Formula:C43H53N11O5Molecular weight:803.95
