CAS 3081389-07-0

Formula: C26H26FN5O

InChI: InChI=1S/C26H26FN5O/c1-3-31(4-2)20-13-23(26-24(14-20)28-10-11-29-26)18-8-9-25(30-15-18)32-16-22(17-32)33-21-7-5-6-19(27)12-21/h5-15,22H,3-4,16-17H2,1-2H3

InChI key: GPUKWSSROXJASR-UHFFFAOYSA-N

SMILES: CCN(CC)C1=CC2=NC=CN=C2C(=C1)C3=CN=C(C=C3)N4CC(C4)OC5=CC(=CC=C5)F

RET-IN-30

CAS: 3081389-07-0

RET-IN-30 (Compound 28) is a RET inhibitor that exhibits inhibitory activity against both wild-type RET and some of its mutants. It is capable of inhibiting the proliferation of A549 cells and demonstrates antitumor properties.

Formula: C₂₆H₂₆FN₅O

Color and Shape: Solid

Molecular weight: 443.52

Ref: TM-T210589